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51 results

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Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
van de Veerdonk FL, Renga G, Pariano M, Bellet MM, Servillo G, Fallarino F, De Luca A, Iannitti RG, Piobbico D, Gargaro M, Manni G, D'Onofrio F, Stincardini C, Sforna L, Borghi M, Castelli M, Pieroni S, Oikonomou V, Villella VR, Puccetti M, Giovagnoli S, Galarini R, Barola C, Maiuri L, Della Fazia MA, Cellini B, Talesa VN, Dinarello CA, Costantini C, Romani L. van de Veerdonk FL, et al. Among authors: villella vr. J Clin Invest. 2022 Jan 18;132(2):e144983. doi: 10.1172/JCI144983. J Clin Invest. 2022. PMID: 34847078 Free PMC article.
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Among authors: villella vr. Nat Cell Biol. 2010 Sep;12(9):863-75. doi: 10.1038/ncb2090. Epub 2010 Aug 15. Nat Cell Biol. 2010. PMID: 20711182
Cystic fibrosis: a disorder with defective autophagy.
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina DL, Settembre C, Gavina M, Raia V, Ballabio A, Maiuri L. Luciani A, et al. Among authors: villella vr. Autophagy. 2011 Jan;7(1):104-6. doi: 10.4161/auto.7.1.13987. Epub 2011 Jan 1. Autophagy. 2011. PMID: 21048426
Nebulized hyaluronan ameliorates lung inflammation in cystic fibrosis mice.
Gavina M, Luciani A, Villella VR, Esposito S, Ferrari E, Bressani I, Casale A, Bruscia EM, Maiuri L, Raia V. Gavina M, et al. Among authors: villella vr. Pediatr Pulmonol. 2013 Aug;48(8):761-71. doi: 10.1002/ppul.22637. Epub 2012 Jul 23. Pediatr Pulmonol. 2013. PMID: 22825912
Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.
Luciani A, Villella VR, Esposito S, Gavina M, Russo I, Silano M, Guido S, Pettoello-Mantovani M, Carnuccio R, Scholte B, De Matteis A, Maiuri MC, Raia V, Luini A, Kroemer G, Maiuri L. Luciani A, et al. Among authors: villella vr. Autophagy. 2012 Nov;8(11):1657-72. doi: 10.4161/auto.21483. Epub 2012 Aug 9. Autophagy. 2012. PMID: 22874563 Free PMC article.
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
De Stefano D, Villella VR, Esposito S, Tosco A, Sepe A, De Gregorio F, Salvadori L, Grassia R, Leone CA, De Rosa G, Maiuri MC, Pettoello-Mantovani M, Guido S, Bossi A, Zolin A, Venerando A, Pinna LA, Mehta A, Bona G, Kroemer G, Maiuri L, Raia V. De Stefano D, et al. Among authors: villella vr. Autophagy. 2014;10(11):2053-74. doi: 10.4161/15548627.2014.973737. Autophagy. 2014. PMID: 25350163 Free PMC article. Clinical Trial.
51 results