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Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival.
Juan-Mateu J, Rech TH, Villate O, Lizarraga-Mollinedo E, Wendt A, Turatsinze JV, Brondani LA, Nardelli TR, Nogueira TC, Esguerra JLS, Alvelos MI, Marchetti P, Eliasson L, Eizirik DL. Juan-Mateu J, et al. Among authors: villate o. J Biol Chem. 2017 Feb 24;292(8):3466-3480. doi: 10.1074/jbc.M116.748335. Epub 2017 Jan 11. J Biol Chem. 2017. PMID: 28077579 Free PMC article.
GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.
Nogueira TC, Paula FM, Villate O, Colli ML, Moura RF, Cunha DA, Marselli L, Marchetti P, Cnop M, Julier C, Eizirik DL. Nogueira TC, et al. Among authors: villate o. PLoS Genet. 2013 May;9(5):e1003532. doi: 10.1371/journal.pgen.1003532. Epub 2013 May 30. PLoS Genet. 2013. PMID: 23737756 Free PMC article.
Nova1 is a master regulator of alternative splicing in pancreatic beta cells.
Villate O, Turatsinze JV, Mascali LG, Grieco FA, Nogueira TC, Cunha DA, Nardelli TR, Sammeth M, Salunkhe VA, Esguerra JL, Eliasson L, Marselli L, Marchetti P, Eizirik DL. Villate O, et al. Nucleic Acids Res. 2014 Oct;42(18):11818-30. doi: 10.1093/nar/gku861. Epub 2014 Sep 23. Nucleic Acids Res. 2014. PMID: 25249621 Free PMC article.
MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.
Grieco FA, Sebastiani G, Juan-Mateu J, Villate O, Marroqui L, Ladrière L, Tugay K, Regazzi R, Bugliani M, Marchetti P, Dotta F, Eizirik DL. Grieco FA, et al. Among authors: villate o. Diabetes. 2017 Jan;66(1):100-112. doi: 10.2337/db16-0592. Epub 2016 Oct 13. Diabetes. 2017. PMID: 27737950 Free PMC article.
RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Cnop M, Abdulkarim B, Bottu G, Cunha DA, Igoillo-Esteve M, Masini M, Turatsinze JV, Griebel T, Villate O, Santin I, Bugliani M, Ladriere L, Marselli L, McCarthy MI, Marchetti P, Sammeth M, Eizirik DL. Cnop M, et al. Among authors: villate o. Diabetes. 2014 Jun;63(6):1978-93. doi: 10.2337/db13-1383. Epub 2013 Dec 30. Diabetes. 2014. PMID: 24379348
A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.
Balhuizen A, Massa S, Mathijs I, Turatsinze JV, De Vos J, Demine S, Xavier C, Villate O, Millard I, Egrise D, Capito C, Scharfmann R, In't Veld P, Marchetti P, Muyldermans S, Goldman S, Lahoutte T, Bouwens L, Eizirik DL, Devoogdt N. Balhuizen A, et al. Among authors: villate o. Sci Rep. 2017 Nov 9;7(1):15130. doi: 10.1038/s41598-017-15417-2. Sci Rep. 2017. PMID: 29123178 Free PMC article.
30 results