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Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties.
Fernández-Bachiller MI, Pérez C, Campillo NE, Páez JA, González-Muñoz GC, Usán P, García-Palomero E, López MG, Villarroya M, García AG, Martínez A, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. Among authors: villarroya m. ChemMedChem. 2009 May;4(5):828-41. doi: 10.1002/cmdc.200800414. ChemMedChem. 2009. PMID: 19308922
New multipotent tetracyclic tacrines with neuroprotective activity.
Marco-Contelles J, León R, de los Ríos C, García AG, López MG, Villarroya M. Marco-Contelles J, et al. Among authors: villarroya m. Bioorg Med Chem. 2006 Dec 15;14(24):8176-85. doi: 10.1016/j.bmc.2006.09.025. Epub 2006 Sep 26. Bioorg Med Chem. 2006. PMID: 17005406
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Marco-Contelles J, León R, de los Ríos C, Samadi A, Bartolini M, Andrisano V, Huertas O, Barril X, Luque FJ, Rodríguez-Franco MI, López B, López MG, García AG, Carreiras Mdo C, Villarroya M. Marco-Contelles J, et al. Among authors: villarroya m. J Med Chem. 2009 May 14;52(9):2724-32. doi: 10.1021/jm801292b. J Med Chem. 2009. PMID: 19374444
Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI. Fernández-Bachiller MI, et al. Among authors: villarroya m. J Med Chem. 2010 Jul 8;53(13):4927-37. doi: 10.1021/jm100329q. J Med Chem. 2010. PMID: 20545360
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
González-Muñoz GC, Arce MP, López B, Pérez C, Romero A, del Barrio L, Martín-de-Saavedra MD, Egea J, León R, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. González-Muñoz GC, et al. Among authors: villarroya m. Eur J Med Chem. 2011 Jun;46(6):2224-35. doi: 10.1016/j.ejmech.2011.03.003. Epub 2011 Mar 21. Eur J Med Chem. 2011. PMID: 21420206
102 results