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Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice.
Pastor-Fernández A, Bertos AR, Sierra-Ramírez A, Del Moral-Salmoral J, Merino J, de Ávila AI, Olagüe C, Villares R, González-Aseguinolaza G, Rodríguez MÁ, Fresno M, Gironés N, Bustos M, Smerdou C, Fernandez-Marcos PJ, von Kobbe C. Pastor-Fernández A, et al. Among authors: villares r. Aging Cell. 2023 Mar;22(3):e13771. doi: 10.1111/acel.13771. Epub 2023 Jan 26. Aging Cell. 2023. PMID: 36704839 Free PMC article.
Growth hormone prevents the development of autoimmune diabetes.
Villares R, Kakabadse D, Juarranz Y, Gomariz RP, Martínez-A C, Mellado M. Villares R, et al. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):E4619-27. doi: 10.1073/pnas.1314985110. Epub 2013 Nov 11. Proc Natl Acad Sci U S A. 2013. PMID: 24218587 Free PMC article.
Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner.
Soler Palacios B, Nieto C, Fajardo P, González de la Aleja A, Andrés N, Dominguez-Soto Á, Lucas P, Cuenda A, Rodríguez-Frade JM, Martínez-A C, Villares R, Corbí ÁL, Mellado M. Soler Palacios B, et al. Among authors: villares r. J Immunol. 2020 Aug 1;205(3):776-788. doi: 10.4049/jimmunol.1901330. Epub 2020 Jun 26. J Immunol. 2020. PMID: 32591394
Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming.
Soler Palacios B, Villares R, Lucas P, Rodríguez-Frade JM, Cayuela A, Piccirillo JG, Lombardía M, Delgado Gestoso D, Fernández-García M, Risco C, Barbas C, Corrales F, Sorzano COS, Martínez-Martín N, Conesa JJ, Iborra FJ, Mellado M. Soler Palacios B, et al. Among authors: villares r. Front Immunol. 2023 Jul 5;14:1200259. doi: 10.3389/fimmu.2023.1200259. eCollection 2023. Front Immunol. 2023. PMID: 37475858 Free PMC article.
Control of T helper 2 cell function and allergic airway inflammation by PKCzeta.
Martin P, Villares R, Rodriguez-Mascarenhas S, Zaballos A, Leitges M, Kovac J, Sizing I, Rennert P, Márquez G, Martínez-A C, Diaz-Meco MT, Moscat J. Martin P, et al. Among authors: villares r. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9866-71. doi: 10.1073/pnas.0501202102. Epub 2005 Jun 29. Proc Natl Acad Sci U S A. 2005. PMID: 15987782 Free PMC article.
38 results