Villar SS - Search Results

1

A novel statistical test for treatment differences in clinical trials using a response-adaptive forward-looking Gittins Index Rule.

Barnett HY, Villar SS, Geys H, Jaki T. Barnett HY, et al. Among authors: villar ss. Biometrics. 2023 Mar;79(1):86-97. doi: 10.1111/biom.13581. Epub 2021 Nov 8. Biometrics. 2023. PMID: 34669968 Free PMC article.

2

Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule.

Villar SS, Wason J, Bowden J. Villar SS, et al. Biometrics. 2015 Dec;71(4):969-78. doi: 10.1111/biom.12337. Epub 2015 Jun 22. Biometrics. 2015. PMID: 26098023 Free PMC article.

3

A Bayesian adaptive design for clinical trials in rare diseases.

Williamson SF, Jacko P, Villar SS, Jaki T. Williamson SF, et al. Among authors: villar ss. Comput Stat Data Anal. 2017 Sep;113:136-153. doi: 10.1016/j.csda.2016.09.006. Epub 2016 Sep 28. Comput Stat Data Anal. 2017. PMID: 28630525 Free PMC article.

4

Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule.

Villar SS, Rosenberger WF. Villar SS, et al. Biometrics. 2018 Mar;74(1):49-57. doi: 10.1111/biom.12738. Epub 2017 Jul 6. Biometrics. 2018. PMID: 28682442 Free PMC article.

5

Adaptive designs in clinical trials: why use them, and how to run and report them.

Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T. Pallmann P, et al. Among authors: villar ss. BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7. BMC Med. 2018. PMID: 29490655 Free PMC article.

6

Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints.

Smith AL, Villar SS. Smith AL, et al. Among authors: villar ss. J Appl Stat. 2018;45(6):1052-1076. doi: 10.1080/02664763.2017.1342780. Epub 2017 Jun 28. J Appl Stat. 2018. PMID: 29551849 Free PMC article.

7

A response-adaptive randomization procedure for multi-armed clinical trials with normally distributed outcomes.

Williamson SF, Villar SS. Williamson SF, et al. Among authors: villar ss. Biometrics. 2020 Mar;76(1):197-209. doi: 10.1111/biom.13119. Epub 2019 Sep 19. Biometrics. 2020. PMID: 31322732 Free PMC article.

8

Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs.

Burnett T, Mozgunov P, Pallmann P, Villar SS, Wheeler GM, Jaki T. Burnett T, et al. Among authors: villar ss. BMC Med. 2020 Nov 19;18(1):352. doi: 10.1186/s12916-020-01808-2. BMC Med. 2020. PMID: 33208155 Free PMC article. Clinical Trial.

9

Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project.

Wilson N, Biggs K, Bowden S, Brown J, Dimairo M, Flight L, Hall J, Hockaday A, Jaki T, Lowe R, Murphy C, Pallmann P, Pilling MA, Snowdon C, Sydes MR, Villar SS, Weir CJ, Welburn J, Yap C, Maier R, Hancock H, Wason JMS. Wilson N, et al. Among authors: villar ss. BMC Med. 2021 Oct 26;19(1):251. doi: 10.1186/s12916-021-02124-z. BMC Med. 2021. PMID: 34696781 Free PMC article.

10

Practical guidance for planning resources required to support publicly-funded adaptive clinical trials.

Wason JMS, Dimairo M, Biggs K, Bowden S, Brown J, Flight L, Hall J, Jaki T, Lowe R, Pallmann P, Pilling MA, Snowdon C, Sydes MR, Villar SS, Weir CJ, Wilson N, Yap C, Hancock H, Maier R. Wason JMS, et al. Among authors: villar ss. BMC Med. 2022 Aug 10;20(1):254. doi: 10.1186/s12916-022-02445-7. BMC Med. 2022. PMID: 35945610 Free PMC article.

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