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Polo-like Kinase 1 Inhibition as a Therapeutic Approach to Selectively Target BRCA1-Deficient Cancer Cells by Synthetic Lethality Induction.
Clin Cancer Res. 2019 Jul 1;25(13):4049-4062. doi: 10.1158/1078-0432.CCR-18-3516. Epub 2019 Mar 19.
Clin Cancer Res. 2019.
PMID: 30890549
AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress.
Villafañez F, García IA, Carbajosa S, Pansa MF, Mansilla S, Llorens MC, Angiolini V, Guantay L, Jacobs H, Madauss KP, Gloger I, Gottifredi V, Bocco JL, Soria G.
Villafañez F, et al.
Oncogene. 2019 May;38(22):4310-4324. doi: 10.1038/s41388-019-0724-7. Epub 2019 Jan 31.
Oncogene. 2019.
PMID: 30705406
Free PMC article.
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Development and Optimization of a Miniaturized Western Blot-Based Screening Platform to Identify Regulators of Post-Translational Modifications.
Villafañez F, Gottifredi V, Soria G.
Villafañez F, et al.
High Throughput. 2019 Jun 3;8(2):15. doi: 10.3390/ht8020015.
High Throughput. 2019.
PMID: 31163614
Free PMC article.
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P53 tumor suppressor is required for efficient execution of the death program following treatment with a cytotoxic limonoid obtained from Melia azedarach.
Joray MB, Villafañez F, González ML, Crespo MI, Laiolo J, Palacios SM, Bocco JL, Soria G, Carpinella MC.
Joray MB, et al. Among authors: villafanez f.
Food Chem Toxicol. 2017 Nov;109(Pt 2):888-897. doi: 10.1016/j.fct.2017.04.039. Epub 2017 Apr 29.
Food Chem Toxicol. 2017.
PMID: 28465189
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GSK-3 is an RNA polymerase II phospho-CTD kinase.
Nieto Moreno N, Villafañez F, Giono LE, Cuenca C, Soria G, Muñoz MJ, Kornblihtt AR.
Nieto Moreno N, et al. Among authors: villafanez f.
Nucleic Acids Res. 2020 Jun 19;48(11):6068-6080. doi: 10.1093/nar/gkaa322.
Nucleic Acids Res. 2020.
PMID: 32374842
Free PMC article.
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Eukaryotic stress-induced mutagenesis is limited by a local control of translesion synthesis.
Masłowska KH, Villafañez F, Laureti L, Iwai S, Pagès V.
Masłowska KH, et al. Among authors: villafanez f.
Nucleic Acids Res. 2022 Feb 28;50(4):2074-2080. doi: 10.1093/nar/gkac044.
Nucleic Acids Res. 2022.
PMID: 35104879
Free PMC article.
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