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Development of an intermediate chromatography step in an insulin purification process. The use of a High Throughput Process Development approach based on selectivity parameters.
Heldin E, Grönlund S, Shanagar J, Hallgren E, Eriksson K, Xavier M, Tunes H, Vilela L. Heldin E, et al. Among authors: vilela l. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 15;973C:126-132. doi: 10.1016/j.jchromb.2014.09.024. Epub 2014 Sep 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 25464105
Recombinant human insulin. VIII. Isolation of fusion protein--S-sulfonate, biotechnological precursor of human insulin, from the biomass of transformed Escherichia coli cells.
Tikhonov RV, Pechenov SE, Belacheu IA, Yakimov SA, Klyushnichenko VE, Boldireva EF, Korobko VG, Tunes H, Thiemann JE, Vilela L, Wulfson AN. Tikhonov RV, et al. Among authors: vilela l. Protein Expr Purif. 2001 Feb;21(1):176-82. doi: 10.1006/prep.2000.1345. Protein Expr Purif. 2001. PMID: 11162404
Microencapsulation and tissue engineering as an alternative treatment of diabetes.
Maria-Engler SS, Mares-Guia M, Correa ML, Oliveira EM, Aita CA, Krogh K, Genzini T, Miranda MP, Ribeiro M, Vilela L, Noronha IL, Eliaschewitz FG, Sogayar MC. Maria-Engler SS, et al. Among authors: vilela l. Braz J Med Biol Res. 2001 Jun;34(6):691-7. doi: 10.1590/s0100-879x2001000600001. Braz J Med Biol Res. 2001. PMID: 11378656 Free article. Review.
Co-localization of nestin and insulin and expression of islet cell markers in long-term human pancreatic nestin-positive cell cultures.
Maria-Engler SS, Corrêa-Giannella ML, Labriola L, Krogh K, Colin C, Lojudice FH, Aita CA, de Oliveira EM, Corrêa TC, da Silva IC, Genzini T, de Miranda MP, Noronha IL, Vilela L, Coimbra CN, Mortara RA, Guia MM, Eliaschewitz FG, Sogayar MC. Maria-Engler SS, et al. Among authors: vilela l. J Endocrinol. 2004 Dec;183(3):455-67. doi: 10.1677/joe.1.05703. J Endocrinol. 2004. PMID: 15590972
Solution structure of human proinsulin C-peptide.
Munte CE, Vilela L, Kalbitzer HR, Garratt RC. Munte CE, et al. Among authors: vilela l. FEBS J. 2005 Aug;272(16):4284-93. doi: 10.1111/j.1742-4658.2005.04843.x. FEBS J. 2005. PMID: 16098208 Free article.
Molecular dynamics and circular dichroism studies of human and rat C-peptides.
Mares-Guia TR, Maigret B, Martins NF, Maia AL, Vilela L, Ramos CH, Neto LJ, Juliano MA, dos Mares-Guia ML, Santoro MM. Mares-Guia TR, et al. Among authors: vilela l. J Mol Graph Model. 2006 Dec;25(4):532-42. doi: 10.1016/j.jmgm.2006.03.002. Epub 2006 Jun 5. J Mol Graph Model. 2006. PMID: 16750642
78 results