Vildhede A - Search Results

1

Understanding Statin-Roxadustat Drug-Drug-Disease Interaction Using Physiologically-Based Pharmacokinetic Modeling.

Dong J, Prieto Garcia L, Huang Y, Tang W, Lundahl A, Elebring M, Ahlström C, Vildhede A, Sjögren E, Någård M. Dong J, et al. Among authors: vildhede a. Clin Pharmacol Ther. 2023 Oct;114(4):825-835. doi: 10.1002/cpt.2980. Epub 2023 Jul 13. Clin Pharmacol Ther. 2023. PMID: 37376792

2

Quantitative Proteomics and Mechanistic Modeling of Transporter-Mediated Disposition in Nonalcoholic Fatty Liver Disease.

Vildhede A, Kimoto E, Pelis RM, Rodrigues AD, Varma MVS. Vildhede A, et al. Clin Pharmacol Ther. 2020 May;107(5):1128-1137. doi: 10.1002/cpt.1699. Epub 2019 Dec 26. Clin Pharmacol Ther. 2020. PMID: 31630405

3

In Vitro Assessment of the Drug-Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters.

Gopaul VS, Vildhede A, Andersson TB, Erlandsson F, Lee CA, Johansson S, Hilgendorf C. Gopaul VS, et al. Among authors: vildhede a. J Pharmacol Exp Ther. 2021 Aug;378(2):108-123. doi: 10.1124/jpet.121.000549. Epub 2021 Jun 1. J Pharmacol Exp Ther. 2021. PMID: 34074714

4

Does the choice of applied physiologically-based pharmacokinetics platform matter? A case study on simvastatin disposition and drug-drug interaction.

Prieto Garcia L, Lundahl A, Ahlström C, Vildhede A, Lennernäs H, Sjögren E. Prieto Garcia L, et al. Among authors: vildhede a. CPT Pharmacometrics Syst Pharmacol. 2022 Sep;11(9):1194-1209. doi: 10.1002/psp4.12837. Epub 2022 Jul 16. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35722750 Free PMC article.

5

Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins.

Prieto Garcia L, Vildhede A, Nordell P, Ahlström C, Montaser AB, Terasaki T, Lennernäs H, Sjögren E. Prieto Garcia L, et al. Among authors: vildhede a. CPT Pharmacometrics Syst Pharmacol. 2024 Apr 4. doi: 10.1002/psp4.13139. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38576225 Free article.

6

Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug.

Bi YA, Mathialagan S, Tylaska L, Fu M, Keefer J, Vildhede A, Costales C, Rodrigues AD, Varma MVS. Bi YA, et al. Among authors: vildhede a. J Pharmacol Exp Ther. 2018 Mar;364(3):390-398. doi: 10.1124/jpet.117.245951. Epub 2018 Jan 11. J Pharmacol Exp Ther. 2018. PMID: 29326367

7

Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies.

Kanebratt KP, Janefeldt A, Vilén L, Vildhede A, Samuelsson K, Milton L, Björkbom A, Persson M, Leandersson C, Andersson TB, Hilgendorf C. Kanebratt KP, et al. Among authors: vildhede a. J Pharm Sci. 2021 Jan;110(1):422-431. doi: 10.1016/j.xphs.2020.10.043. Epub 2020 Oct 26. J Pharm Sci. 2021. PMID: 33122050 Free article.

8

Hepatocyte size fractionation allows dissection of human liver zonation.

Ölander M, Wegler C, Flörkemeier I, Treyer A, Handin N, Pedersen JM, Vildhede A, Mateus A, LeCluyse EL, Urdzik J, Artursson P. Ölander M, et al. Among authors: vildhede a. J Cell Physiol. 2021 Aug;236(8):5885-5894. doi: 10.1002/jcp.30273. Epub 2021 Jan 16. J Cell Physiol. 2021. PMID: 33452735

9

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Karlgren M, Vildhede A, Norinder U, Wisniewski JR, Kimoto E, Lai Y, Haglund U, Artursson P. Karlgren M, et al. Among authors: vildhede a. J Med Chem. 2012 May 24;55(10):4740-63. doi: 10.1021/jm300212s. Epub 2012 May 15. J Med Chem. 2012. PMID: 22541068 Free PMC article.

10

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach.

Vildhede A, Mateus A, Khan EK, Lai Y, Karlgren M, Artursson P, Kjellsson MC. Vildhede A, et al. Drug Metab Dispos. 2016 Apr;44(4):505-16. doi: 10.1124/dmd.115.066746. Epub 2016 Feb 3. Drug Metab Dispos. 2016. PMID: 26842596

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

21 results

Search Page