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Drug repurposing of dopaminergic drugs to inhibit ataxin-3 aggregation.
Figueiredo F, Sárkány Z, Silva A, Vilasboas-Campos D, Maciel P, Teixeira-Castro A, Martins PM, Macedo-Ribeiro S. Figueiredo F, et al. Among authors: vilasboas campos d. Biomed Pharmacother. 2023 Sep;165:115258. doi: 10.1016/j.biopha.2023.115258. Epub 2023 Aug 5. Biomed Pharmacother. 2023. PMID: 37549460 Free article.
Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease.
Pereira-Sousa J, Ferreira-Lomba B, Bellver-Sanchis A, Vilasboas-Campos D, Fernandes JH, Costa MD, Varney MA, Newman-Tancredi A, Maciel P, Teixeira-Castro A. Pereira-Sousa J, et al. Among authors: vilasboas campos d. Neurobiol Dis. 2021 May;152:105278. doi: 10.1016/j.nbd.2021.105278. Epub 2021 Jan 28. Neurobiol Dis. 2021. PMID: 33516872 Free article.
Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D2 and Serotonin 1A and 2A Receptors in C. elegans.
Jalles A, Vieira C, Pereira-Sousa J, Vilasboas-Campos D, Mota AF, Vasconcelos S, Ferreira-Lomba B, Costa MD, Da Silva JD, Maciel P, Teixeira-Castro A. Jalles A, et al. Among authors: vilasboas campos d. Biomedicines. 2022 Feb 3;10(2):370. doi: 10.3390/biomedicines10020370. Biomedicines. 2022. PMID: 35203579 Free PMC article.
Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing.
Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M. Raposo M, et al. Among authors: vilasboas campos d. Neurobiol Dis. 2022 Jan;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 3. Neurobiol Dis. 2022. PMID: 34871736 Free article.
Differential impact of diesel exhaust particles on glutamatergic and dopaminergic neurons in Caenorhabditis elegans: A neurodegenerative perspective.
Chatterjee N, González-Durruthy M, Costa MD, Ribeiro AR, Vilas-Boas V, Vilasboas-Campos D, Maciel P, Alfaro-Moreno E. Chatterjee N, et al. Among authors: vilasboas campos d. Environ Int. 2024 Apr;186:108597. doi: 10.1016/j.envint.2024.108597. Epub 2024 Mar 22. Environ Int. 2024. PMID: 38579453 Free article.
Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3.
Duarte-Silva S, Da Silva JD, Monteiro-Fernandes D, Costa MD, Neves-Carvalho A, Raposo M, Soares-Cunha C, Correia JS, Nogueira-Goncalves G, Fernandes HS, Oliveira S, Ferreira-Fernandes AR, Rodrigues F, Pereira-Sousa J, Vilasboas-Campos D, Guerreiro S, Campos J, Meireles-Costa L, Rodrigues CMP, Cabantous S, Sousa SF, Lima M, Teixeira-Castro A, Maciel P. Duarte-Silva S, et al. Among authors: vilasboas campos d. J Clin Invest. 2024 Mar 1;134(5):e162246. doi: 10.1172/JCI162246. J Clin Invest. 2024. PMID: 38227368 Free PMC article.