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Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.
Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, Bahar I, Vilardaga JP. Clark LJ, et al. Among authors: vilardaga jp. Nat Chem Biol. 2020 Oct;16(10):1096-1104. doi: 10.1038/s41589-020-0567-0. Epub 2020 Jul 6. Nat Chem Biol. 2020. PMID: 32632293 Free PMC article.
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.
Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP. Ferrandon S, et al. Among authors: vilardaga jp. Nat Chem Biol. 2009 Oct;5(10):734-42. doi: 10.1038/nchembio.206. Epub 2009 Aug 23. Nat Chem Biol. 2009. PMID: 19701185 Free PMC article.
Retromer terminates the generation of cAMP by internalized PTH receptors.
Feinstein TN, Wehbi VL, Ardura JA, Wheeler DS, Ferrandon S, Gardella TJ, Vilardaga JP. Feinstein TN, et al. Among authors: vilardaga jp. Nat Chem Biol. 2011 May;7(5):278-84. doi: 10.1038/nchembio.545. Epub 2011 Mar 27. Nat Chem Biol. 2011. PMID: 21445058 Free PMC article.
Non-canonical signaling of the PTH receptor.
Vilardaga JP, Gardella TJ, Wehbi VL, Feinstein TN. Vilardaga JP, et al. Trends Pharmacol Sci. 2012 Aug;33(8):423-31. doi: 10.1016/j.tips.2012.05.004. Epub 2012 Jun 16. Trends Pharmacol Sci. 2012. PMID: 22709554 Free PMC article. Review.
Noncanonical GPCR signaling arising from a PTH receptor-arrestin-Gβγ complex.
Wehbi VL, Stevenson HP, Feinstein TN, Calero G, Romero G, Vilardaga JP. Wehbi VL, et al. Among authors: vilardaga jp. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1530-5. doi: 10.1073/pnas.1205756110. Epub 2013 Jan 7. Proc Natl Acad Sci U S A. 2013. PMID: 23297229 Free PMC article.
Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase.
Gidon A, Al-Bataineh MM, Jean-Alphonse FG, Stevenson HP, Watanabe T, Louet C, Khatri A, Calero G, Pastor-Soler NM, Gardella TJ, Vilardaga JP. Gidon A, et al. Among authors: vilardaga jp. Nat Chem Biol. 2014 Sep;10(9):707-9. doi: 10.1038/nchembio.1589. Epub 2014 Jul 27. Nat Chem Biol. 2014. PMID: 25064832 Free PMC article.
96 results