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243 results

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Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation.
Poplaski V, Bomidi C, Kambal A, Nguyen-Phuc H, Di Rienzi SC, Danhof HA, Zeng XL, Feagins LA, Deng N, Vilar E, McAllister F, Coarfa C, Min S, Kim HJ, Shukla R, Britton R, Estes MK, Blutt SE. Poplaski V, et al. Among authors: vilar e. J Clin Invest. 2023 Nov 1;133(21):e166884. doi: 10.1172/JCI166884. J Clin Invest. 2023. PMID: 37909332 Free PMC article.
Genomic Landscape of Colorectal Mucosa and Adenomas.
Borras E, San Lucas FA, Chang K, Zhou R, Masand G, Fowler J, Mork ME, You YN, Taggart MW, McAllister F, Jones DA, Davies GE, Edelmann W, Ehli EA, Lynch PM, Hawk ET, Capella G, Scheet P, Vilar E. Borras E, et al. Among authors: vilar e. Cancer Prev Res (Phila). 2016 Jun;9(6):417-27. doi: 10.1158/1940-6207.CAPR-16-0081. Epub 2016 May 24. Cancer Prev Res (Phila). 2016. PMID: 27221540 Free PMC article.
Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.
Chang K, Taggart MW, Reyes-Uribe L, Borras E, Riquelme E, Barnett RM, Leoni G, San Lucas FA, Catanese MT, Mori F, Diodoro MG, You YN, Hawk ET, Roszik J, Scheet P, Kopetz S, Nicosia A, Scarselli E, Lynch PM, McAllister F, Vilar E. Chang K, et al. Among authors: vilar e. JAMA Oncol. 2018 Aug 1;4(8):1085-1092. doi: 10.1001/jamaoncol.2018.1482. JAMA Oncol. 2018. PMID: 29710228 Free PMC article.
High Prevalence of Hereditary Cancer Syndromes and Outcomes in Adults with Early-Onset Pancreatic Cancer.
Bannon SA, Montiel MF, Goldstein JB, Dong W, Mork ME, Borras E, Hasanov M, Varadhachary GR, Maitra A, Katz MH, Feng L, Futreal A, Fogelman DR, Vilar E, McAllister F. Bannon SA, et al. Among authors: vilar e. Cancer Prev Res (Phila). 2018 Nov;11(11):679-686. doi: 10.1158/1940-6207.CAPR-18-0014. Epub 2018 Oct 1. Cancer Prev Res (Phila). 2018. PMID: 30274973 Free PMC article.
Telomere dysfunction activates YAP1 to drive tissue inflammation.
Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, Liao WT, Whitley EM, Dey P, Hou P, LaBella KA, Chang A, Wang G, Spring DJ, Deng P, Zhao D, Liang X, Lan Z, Lin Y, Sarkar S, Terranova C, Deribe YL, Blutt SE, Okhuysen P, Zhang J, Vilar E, Nielsen OH, Dupont A, Younes M, Patel KR, Shroyer NF, Rai K, Estes MK, Wang YA, Bertuch AA, DePinho RA. Chakravarti D, et al. Among authors: vilar e. Nat Commun. 2020 Sep 21;11(1):4766. doi: 10.1038/s41467-020-18420-w. Nat Commun. 2020. PMID: 32958778 Free PMC article.
Telomere dysfunction instigates inflammation in inflammatory bowel disease.
Chakravarti D, Lee R, Multani AS, Santoni A, Keith Z, Hsu WH, Chang K, Reyes L, Rashid A, Wu CJ, Li J, Zhang J, Shim HS, Chandra K, Deng P, Spring DJ, Nielsen OH, Riis LB, Mayigegowda KK, Blutt SE, Zhang J, Younes M, DuPont A, Thirumurthi S, Vilar E, Estes MK, Colla S, Shroyer NF, DePinho RA. Chakravarti D, et al. Among authors: vilar e. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2024853118. doi: 10.1073/pnas.2024853118. Proc Natl Acad Sci U S A. 2021. PMID: 34253611 Free PMC article.
Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer.
Ozirmak Lermi N, Gray SB, Bowen CM, Reyes-Uribe L, Dray BK, Deng N, Harris RA, Raveendran M, Benavides F, Hodo CL, Taggart MW, Colbert Maresso K, Sinha KM, Rogers J, Vilar E. Ozirmak Lermi N, et al. Among authors: vilar e. PLoS Genet. 2022 Apr 21;18(4):e1010163. doi: 10.1371/journal.pgen.1010163. eCollection 2022 Apr. PLoS Genet. 2022. PMID: 35446842 Free PMC article.
Naproxen chemoprevention induces proliferation of cytotoxic lymphocytes in Lynch Syndrome colorectal mucosa.
Bowen CM, Deng N, Reyes-Uribe L, Parra ER, Rocha P, Solis LM, Wistuba II, Sepeda VO, Vornik L, Perloff M, Szabo E, Umar A, Sinha KM, Brown PH, Vilar E. Bowen CM, et al. Among authors: vilar e. Front Immunol. 2023 May 3;14:1162669. doi: 10.3389/fimmu.2023.1162669. eCollection 2023. Front Immunol. 2023. PMID: 37207208 Free PMC article. Clinical Trial.
243 results