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Telomere dysfunction activates YAP1 to drive tissue inflammation.
Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, Liao WT, Whitley EM, Dey P, Hou P, LaBella KA, Chang A, Wang G, Spring DJ, Deng P, Zhao D, Liang X, Lan Z, Lin Y, Sarkar S, Terranova C, Deribe YL, Blutt SE, Okhuysen P, Zhang J, Vilar E, Nielsen OH, Dupont A, Younes M, Patel KR, Shroyer NF, Rai K, Estes MK, Wang YA, Bertuch AA, DePinho RA. Chakravarti D, et al. Among authors: vilar e. Nat Commun. 2020 Sep 21;11(1):4766. doi: 10.1038/s41467-020-18420-w. Nat Commun. 2020. PMID: 32958778 Free PMC article.
Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis.
Bowen CM, Walter L, Borras E, Wu W, Ozcan Z, Chang K, Bommi PV, Taggart MW, Thirumurthi S, Lynch PM, Reyes-Uribe L, Scheet PA, Sinha KM, Vilar E. Bowen CM, et al. Among authors: vilar e. Cancer Prev Res (Phila). 2021 Sep;14(9):851-862. doi: 10.1158/1940-6207.CAPR-20-0496. Epub 2021 Jul 15. Cancer Prev Res (Phila). 2021. PMID: 34266857 Free PMC article.
Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination.
Simmons K, Thomas JV, Ludford K, Willis JA, Higbie VS, Raghav KPS, Johnson B, Dasari A, Kee BK, Parseghian CM, Lee MS, Le PH, Morelli MP, Shen JP, Bent A, Vilar E, Wolff RA, Kopetz S, Overman MJ, Morris VK. Simmons K, et al. Among authors: vilar e. Cancer Res Commun. 2023 Dec 11;3(12):2510-2517. doi: 10.1158/2767-9764.CRC-23-0340. Cancer Res Commun. 2023. PMID: 38085001 Free PMC article.
Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition.
Rajendran P, Johnson G, Li L, Chen YS, Dashwood M, Nguyen N, Ulusan A, Ertem F, Zhang M, Li J, Sun D, Huang Y, Wang S, Leung HC, Lieberman D, Beaver L, Ho E, Bedford M, Chang K, Vilar E, Dashwood R. Rajendran P, et al. Among authors: vilar e. Cancer Res. 2019 Mar 1;79(5):918-927. doi: 10.1158/0008-5472.CAN-18-2003. Epub 2019 Jan 14. Cancer Res. 2019. PMID: 30643017 Free PMC article.
The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
Bommi PV, Bowen CM, Reyes-Uribe L, Wu W, Katayama H, Rocha P, Parra ER, Francisco-Cruz A, Ozcan Z, Tosti E, Willis JA, Wu H, Taggart MW, Burks JK, Lynch PM, Edelmann W, Scheet PA, Wistuba II, Sinha KM, Hanash SM, Vilar E. Bommi PV, et al. Among authors: vilar e. Cancer Res. 2021 May 15;81(10):2760-2773. doi: 10.1158/0008-5472.CAN-20-2896. Epub 2021 Mar 18. Cancer Res. 2021. PMID: 34003775 Free PMC article.
243 results