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Synthesis of benzopyran derivatives as PPARα and/or PPARγ activators.
Bermejo A, Barrachina I, El Aouad N, Franck X, Chahboune N, Andreu I, Figadère B, Vila L, Hennuyer N, Staels B, Dacquet C, Caignard DH, Sanz MJ, Cortes D, Cabedo N. Bermejo A, et al. Among authors: vila l. Bioorg Med Chem. 2019 Dec 15;27(24):115162. doi: 10.1016/j.bmc.2019.115162. Epub 2019 Oct 30. Bioorg Med Chem. 2019. PMID: 31703893
Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner-Wadsworth-Emmons Olefination with PPARα/γ Agonist Activity.
García A, Vila L, Marín P, Bernabeu Á, Villarroel-Vicente C, Hennuyer N, Staels B, Franck X, Figadère B, Cabedo N, Cortes D. García A, et al. Among authors: vila l. ACS Med Chem Lett. 2021 Oct 6;12(11):1783-1786. doi: 10.1021/acsmedchemlett.1c00400. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795868 Free PMC article.
Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity.
Marques P, Villarroel-Vicente C, Collado A, García A, Vila L, Duplan I, Hennuyer N, Garibotto F, Enriz RD, Dacquet C, Staels B, Piqueras L, Cortes D, Sanz MJ, Cabedo N. Marques P, et al. Among authors: vila l. Pharmacol Res. 2023 Jan;187:106638. doi: 10.1016/j.phrs.2022.106638. Epub 2022 Dec 28. Pharmacol Res. 2023. PMID: 36586645 Free article.
Spatially preserved multi-region transcriptomic subtyping and biomarkers of chemoimmunotherapy outcome in extensive-stage small cell lung cancer.
Peressini M, Garcia-Campelo R, Massuti B, Marti C, Cobo M, Gutiérrez V, Dómine M, Fuentes J, Majem M, de Castro J, Cordoba JF, Diz MP, Isla D, Esteban E, Carcereny E, Vila L, Moreno-Vega A, Ros S, Moreno A, Garcia FJ, Huidobro G, Aguado C, Cebey-Lopez V, Valdivia J, Palmero R, Lianes P, Lopez-Brea M, Vidal OJ, Provencio M, Arriola E, Baena J, Herrera M, Bote H, Molero M, Adradas V, Ponce-Aix S, Nuñez-Buiza A, Ucero Á, Hernandez S, Lopez-Rios F, Conde E, Paz-Ares L, Zugazagoitia J. Peressini M, et al. Among authors: vila l. Clin Cancer Res. 2024 Apr 17. doi: 10.1158/1078-0432.CCR-24-0104. Online ahead of print. Clin Cancer Res. 2024. PMID: 38630755
The S-REAL study: Spanish real-world data on unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy.
Gómez Rueda A, Taus Á, Álvarez Álvarez R, Bernabé-Caro R, Chara L, López-Brea M, Vilà L, Sala González MÁ, Del Barrio Díaz Aldagalán A, Esteban Herrera B, López Castro R, Álvarez Cabellos R, Doménech M, Falagan S, Moreno Vega A, Aguado C, Barba A, Delgado Ureña MT, Isla D, Bellido Hernández L, Fírvida Pérez JL, Juan-Vidal Ó, Massutí B, Mielgo-Rubio X, Ortega AL, Catot S, Dómine M, Escoín-Pérez C, García Navalón F, Gil-Bazo I, Muñoz S, Rodríguez-Abreu D, Villatoro Roldán RM, Alonso-Jáudenes Curbera G, León-Mateos L, Padilla A, Paredes Lario A, Sánchez-Torres JM, Garrido P; Spanish Lung Cancer Group. Gómez Rueda A, et al. Among authors: vila l. Clin Transl Oncol. 2024 Mar 21. doi: 10.1007/s12094-024-03404-9. Online ahead of print. Clin Transl Oncol. 2024. PMID: 38512450
525 results