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The metallo-beta-lactamase GOB is a mono-Zn(II) enzyme with a novel active site.
Morán-Barrio J, González JM, Lisa MN, Costello AL, Peraro MD, Carloni P, Bennett B, Tierney DL, Limansky AS, Viale AM, Vila AJ. Morán-Barrio J, et al. Among authors: vila aj. J Biol Chem. 2007 Jun 22;282(25):18286-18293. doi: 10.1074/jbc.M700467200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403673 Free article.
Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity.
Llarrull LI, Fabiane SM, Kowalski JM, Bennett B, Sutton BJ, Vila AJ. Llarrull LI, et al. Among authors: vila aj. J Biol Chem. 2007 Jun 22;282(25):18276-18285. doi: 10.1074/jbc.M700742200. Epub 2007 Apr 10. J Biol Chem. 2007. PMID: 17426028 Free article.
162 results