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A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.
Vijayan K, Arang N, Wei L, Morrison R, Geiger R, Parks KR, Lewis AJ, Mast FD, Douglass AN, Kain HS, Aitchison JD, Johnson JS, Aderem A, Kaushansky A. Vijayan K, et al. Cell Chem Biol. 2022 Sep 15;29(9):1419-1433.e5. doi: 10.1016/j.chembiol.2022.06.001. Epub 2022 Jun 22. Cell Chem Biol. 2022. PMID: 35738280 Free PMC article.
Liver stage malaria infection is controlled by host regulators of lipid peroxidation.
Kain HS, Glennon EKK, Vijayan K, Arang N, Douglass AN, Fortin CL, Zuck M, Lewis AJ, Whiteside SL, Dudgeon DR, Johnson JS, Aderem A, Stevens KR, Kaushansky A. Kain HS, et al. Among authors: vijayan k. Cell Death Differ. 2020 Jan;27(1):44-54. doi: 10.1038/s41418-019-0338-1. Epub 2019 May 7. Cell Death Differ. 2020. PMID: 31065106 Free PMC article.
A Molecular Signature in Blood Reveals a Role for p53 in Regulating Malaria-Induced Inflammation.
Tran TM, Guha R, Portugal S, Skinner J, Ongoiba A, Bhardwaj J, Jones M, Moebius J, Venepally P, Doumbo S, DeRiso EA, Li S, Vijayan K, Anzick SL, Hart GT, O'Connell EM, Doumbo OK, Kaushansky A, Alter G, Felgner PL, Lorenzi H, Kayentao K, Traore B, Kirkness EF, Crompton PD. Tran TM, et al. Among authors: vijayan k. Immunity. 2019 Oct 15;51(4):750-765.e10. doi: 10.1016/j.immuni.2019.08.009. Epub 2019 Sep 3. Immunity. 2019. PMID: 31492649 Free PMC article.
Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium yoelii liver stage.
Vijayan K, Visweswaran GRR, Chandrasekaran R, Trakhimets O, Brown SL, Watson A, Zuck M, Dambrauskas N, Raappana A, Carbonetti S, Kelnhofer-Millevolte L, Glennon EKK, Postiglione R, Sather DN, Kaushansky A. Vijayan K, et al. Cell Rep. 2021 Aug 3;36(5):109489. doi: 10.1016/j.celrep.2021.109489. Cell Rep. 2021. PMID: 34348141 Free article.
Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection.
Visweswaran GRR, Vijayan K, Chandrasekaran R, Trakhimets O, Brown SL, Vigdorovich V, Yang A, Raappana A, Watson A, Selman W, Zuck M, Dambrauskas N, Kaushansky A, Sather DN. Visweswaran GRR, et al. Among authors: vijayan k. PLoS Pathog. 2022 Jul 6;18(7):e1010671. doi: 10.1371/journal.ppat.1010671. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35793394 Free PMC article.
Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.
Rodríguez-Hernández D, Vijayan K, Zigweid R, Fenwick MK, Sankaran B, Roobsoong W, Sattabongkot J, Glennon EKK, Myler PJ, Sunnerhagen P, Staker BL, Kaushansky A, Grøtli M. Rodríguez-Hernández D, et al. Among authors: vijayan k. Nat Commun. 2023 Sep 5;14(1):5408. doi: 10.1038/s41467-023-41119-7. Nat Commun. 2023. PMID: 37669940 Free PMC article.
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