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A novel proteotoxic stress associated mechanism for macular corneal dystrophy.
Kaarniranta K, Szalai E, Smedowski A, Hegyi Z, Kivinen N, Viiri J, Wowra B, Dobrowolski D, Módis L Jr, Berta A, Wylegala E, Felszeghy S. Kaarniranta K, et al. Among authors: viiri j. Histol Histopathol. 2015 Aug;30(8):921-30. doi: 10.14670/HH-11-588. Epub 2015 Jan 19. Histol Histopathol. 2015. PMID: 25597745
Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells.
Viiri J, Amadio M, Marchesi N, Hyttinen JM, Kivinen N, Sironen R, Rilla K, Akhtar S, Provenzani A, D'Agostino VG, Govoni S, Pascale A, Agostini H, Petrovski G, Salminen A, Kaarniranta K. Viiri J, et al. PLoS One. 2013 Jul 29;8(7):e69563. doi: 10.1371/journal.pone.0069563. Print 2013. PLoS One. 2013. PMID: 23922739 Free PMC article.
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells.
Ryhänen T, Hyttinen JM, Kopitz J, Rilla K, Kuusisto E, Mannermaa E, Viiri J, Holmberg CI, Immonen I, Meri S, Parkkinen J, Eskelinen EL, Uusitalo H, Salminen A, Kaarniranta K. Ryhänen T, et al. Among authors: viiri j. J Cell Mol Med. 2009 Sep;13(9B):3616-31. doi: 10.1111/j.1582-4934.2008.00577.x. Epub 2008 Nov 6. J Cell Mol Med. 2009. PMID: 19017362 Free PMC article.
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K. Felszeghy S, et al. Among authors: viiri j. Redox Biol. 2019 Jan;20:1-12. doi: 10.1016/j.redox.2018.09.011. Epub 2018 Sep 14. Redox Biol. 2019. PMID: 30253279 Free PMC article.
19 results