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Progression of herpesvirus infection remodels mitochondrial organization and metabolism.
Leclerc S, Gupta A, Ruokolainen V, Chen JH, Kunnas K, Ekman AA, Niskanen H, Belevich I, Vihinen H, Turkki P, Perez-Berna AJ, Kapishnikov S, Mäntylä E, Harkiolaki M, Dufour E, Hytönen V, Pereiro E, McEnroe T, Fahy K, Kaikkonen MU, Jokitalo E, Larabell CA, Weinhardt V, Mattola S, Aho V, Vihinen-Ranta M. Leclerc S, et al. Among authors: vihinen h. PLoS Pathog. 2024 Apr 15;20(4):e1011829. doi: 10.1371/journal.ppat.1011829. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38620036 Free PMC article.
Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity.
Paukštytė J, López Cabezas RM, Feng Y, Tong K, Schnyder D, Elomaa E, Gregorova P, Doudin M, Särkkä M, Sarameri J, Lippi A, Vihinen H, Juutila J, Nieminen A, Törönen P, Holm L, Jokitalo E, Krisko A, Huiskonen J, Sarin LP, Hietakangas V, Picotti P, Barral Y, Saarikangas J. Paukštytė J, et al. Among authors: vihinen h. Mol Cell. 2023 Sep 21;83(18):3360-3376.e11. doi: 10.1016/j.molcel.2023.08.015. Epub 2023 Sep 11. Mol Cell. 2023. PMID: 37699397 Free article.
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis.
Hazari Y, Urra H, Garcia Lopez VA, Diaz J, Tamburini G, Milani M, Pihan P, Durand S, Aprahamia F, Baxter R, Huang M, Dong XC, Vihinen H, Batista-Gonzalez A, Godoy P, Criollo A, Ratziu V, Foufelle F, Hengstler JG, Jokitalo E, Bailly-Maitre B, Maiers JL, Plate L, Kroemer G, Hetz C. Hazari Y, et al. Among authors: vihinen h. bioRxiv [Preprint]. 2023 May 2:2023.05.02.538835. doi: 10.1101/2023.05.02.538835. bioRxiv. 2023. PMID: 37205565 Free PMC article. Preprint.
Antibiotic Treatment is an Independent Poor Risk Factor in NSCLC But Not in Melanoma Patients Who had Received Anti-PD-1/L1 Monotherapy.
Vihinen H, Jokinen A, Laajala TD, Wahid N, Peltola L, Kettunen T, Rönkä A, Tiainen L, Skyttä T, Kohtamäki L, Tulokas S, Karhapää H, Hernberg M, Silvoniemi M, Mattila KE. Vihinen H, et al. Clin Lung Cancer. 2023 Jun;24(4):295-304. doi: 10.1016/j.cllc.2023.01.004. Epub 2023 Jan 24. Clin Lung Cancer. 2023. PMID: 36774235 Free article.
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes.
Ignatenko O, Malinen S, Rybas S, Vihinen H, Nikkanen J, Kononov A, Jokitalo ES, Ince-Dunn G, Suomalainen A. Ignatenko O, et al. Among authors: vihinen h. J Cell Biol. 2023 Jan 2;222(1):e202203019. doi: 10.1083/jcb.202203019. Epub 2022 Nov 16. J Cell Biol. 2023. PMID: 36383135 Free PMC article.
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