Vieth M - Search Results

1

Structural determinants of dual incretin receptor agonism by tirzepatide.

Sun B, Willard FS, Feng D, Alsina-Fernandez J, Chen Q, Vieth M, Ho JD, Showalter AD, Stutsman C, Ding L, Suter TM, Dunbar JD, Carpenter JW, Mohammed FA, Aihara E, Brown RA, Bueno AB, Emmerson PJ, Moyers JS, Kobilka TS, Coghlan MP, Kobilka BK, Sloop KW. Sun B, et al. Among authors: vieth m. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2116506119. doi: 10.1073/pnas.2116506119. Epub 2022 Mar 25. Proc Natl Acad Sci U S A. 2022. PMID: 35333651 Free PMC article.

2

Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.

Bueno AB, Sun B, Willard FS, Feng D, Ho JD, Wainscott DB, Showalter AD, Vieth M, Chen Q, Stutsman C, Chau B, Ficorilli J, Agejas FJ, Cumming GR, Jiménez A, Rojo I, Kobilka TS, Kobilka BK, Sloop KW. Bueno AB, et al. Among authors: vieth m. Nat Chem Biol. 2020 Oct;16(10):1105-1110. doi: 10.1038/s41589-020-0589-7. Epub 2020 Jul 20. Nat Chem Biol. 2020. PMID: 32690941

3

Geometric accuracy of three-dimensional molecular overlays.

Chen Q, Higgs RE, Vieth M. Chen Q, et al. Among authors: vieth m. J Chem Inf Model. 2006 Sep-Oct;46(5):1996-2002. doi: 10.1021/ci060134h. J Chem Inf Model. 2006. PMID: 16995730

4

Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averages.

Chen Q, Vieth M, Timm DE, Humblet C, Schneidman-Duhovny D, Chemmama IE, Sali A, Zeng W, Lu J, Liu L. Chen Q, et al. Among authors: vieth m. PLoS One. 2017 Apr 13;12(4):e0175758. doi: 10.1371/journal.pone.0175758. eCollection 2017. PLoS One. 2017. PMID: 28406969 Free PMC article.

5

The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines.

Hamdouchi C, Keyser H, Collins E, Jaramillo C, De Diego JE, Spencer CD, Dempsey JA, Anderson BD, Leggett T, Stamm NB, Schultz RM, Watkins SA, Cocke K, Lemke S, Burke TF, Beckmann RP, Dixon JT, Gurganus TM, Rankl NB, Houck KA, Zhang F, Vieth M, Espinosa J, Timm DE, Campbell RM, Patel BK, Brooks HB. Hamdouchi C, et al. Among authors: vieth m. Mol Cancer Ther. 2004 Jan;3(1):1-9. Mol Cancer Ther. 2004. PMID: 14749470

6

Identification of tyrosine kinase inhibitors that halt Plasmodium falciparum parasitemia.

Kesely K, Noomuna P, Vieth M, Hipskind P, Haldar K, Pantaleo A, Turrini F, Low PS. Kesely K, et al. Among authors: vieth m. PLoS One. 2020 Nov 12;15(11):e0242372. doi: 10.1371/journal.pone.0242372. eCollection 2020. PLoS One. 2020. PMID: 33180822 Free PMC article.

7

Kinomics-structural biology and chemogenomics of kinase inhibitors and targets.

Vieth M, Higgs RE, Robertson DH, Shapiro M, Gragg EA, Hemmerle H. Vieth M, et al. Biochim Biophys Acta. 2004 Mar 11;1697(1-2):243-57. doi: 10.1016/j.bbapap.2003.11.028. Biochim Biophys Acta. 2004. PMID: 15023365 Review.

8

Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.

Vieth M, Erickson J, Wang J, Webster Y, Mader M, Higgs R, Watson I. Vieth M, et al. J Med Chem. 2009 Oct 22;52(20):6456-66. doi: 10.1021/jm901147e. J Med Chem. 2009. PMID: 19791746

9

Structure-guided expansion of kinase fragment libraries driven by support vector machine models.

Erickson JA, Mader MM, Watson IA, Webster YW, Higgs RE, Bell MA, Vieth M. Erickson JA, et al. Among authors: vieth m. Biochim Biophys Acta. 2010 Mar;1804(3):642-52. doi: 10.1016/j.bbapap.2009.12.002. Epub 2009 Dec 11. Biochim Biophys Acta. 2010. PMID: 20005305

10

Characteristic physical properties and structural fragments of marketed oral drugs.

Vieth M, Siegel MG, Higgs RE, Watson IA, Robertson DH, Savin KA, Durst GL, Hipskind PA. Vieth M, et al. J Med Chem. 2004 Jan 1;47(1):224-32. doi: 10.1021/jm030267j. J Med Chem. 2004. PMID: 14695836

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