Viejo L - Search Results

1

Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders.

Espadinha M, Viejo L, Lopes RMRM, Herrera-Arozamena C, Molins E, Dos Santos DJVA, Gonçalves L, Rodríguez-Franco MI, Ríos CL, Santos MMM. Espadinha M, et al. Among authors: viejo l. Eur J Med Chem. 2020 May 15;194:112242. doi: 10.1016/j.ejmech.2020.112242. Epub 2020 Mar 23. Eur J Med Chem. 2020. PMID: 32248004

2

Substituent effect of N-benzylated gramine derivatives that prevent the PP2A inhibition and dissipate the neuronal Ca²⁺ overload, as a multitarget strategy for the treatment of Alzheimer's disease.

Gonzalez D, Arribas RL, Viejo L, Lajarin-Cuesta R, de Los Rios C. Gonzalez D, et al. Among authors: viejo l. Bioorg Med Chem. 2018 May 15;26(9):2551-2560. doi: 10.1016/j.bmc.2018.04.019. Epub 2018 Apr 9. Bioorg Med Chem. 2018. PMID: 29656989

3

C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer's disease targeting tauopathies.

Arribas RL, Viejo L, Bravo I, Martínez M, Ramos E, Romero A, García-Frutos EM, Janssens V, Montiel C, de Los Ríos C. Arribas RL, et al. Among authors: viejo l. Eur J Med Chem. 2023 May 5;251:115245. doi: 10.1016/j.ejmech.2023.115245. Epub 2023 Mar 4. Eur J Med Chem. 2023. PMID: 36905916 Free article.

4

Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca²⁺ Overload for the Treatment of Neurodegenerative Diseases and Stroke.

Viejo L, Rubio-Alarcón M, Arribas RL, Moreno-Castro M, Pérez-Marín R, Braun-Cornejo M, Estrada-Valencia M, de Los Ríos C. Viejo L, et al. Molecules. 2021 Jul 24;26(15):4473. doi: 10.3390/molecules26154473. Molecules. 2021. PMID: 34361628 Free PMC article.

5

(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.

Ismaili L, Monnin J, Etievant A, Arribas RL, Viejo L, Refouvelet B, Soukup O, Janockova J, Hepnarova V, Korabecny J, Kucera T, Jun D, Andrys R, Musilek K, Baguet A, García-Frutos EM, De Simone A, Andrisano V, Bartolini M, de Los Ríos C, Marco-Contelles J, Haffen E. Ismaili L, et al. Among authors: viejo l. ACS Chem Neurosci. 2021 Apr 21;12(8):1328-1342. doi: 10.1021/acschemneuro.0c00803. Epub 2021 Apr 2. ACS Chem Neurosci. 2021. PMID: 33797877

6

Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts.

Bisi A, Feoli A, Trezza A, Viejo L, Formaggio F, Bartolini M, Belluti F, Gobbi S, Spiga O, Caprini M, de Los Rios C, Castellano S, Rampa A. Bisi A, et al. Among authors: viejo l. Bioorg Chem. 2022 Dec;129:106152. doi: 10.1016/j.bioorg.2022.106152. Epub 2022 Sep 16. Bioorg Chem. 2022. PMID: 36155094

7

Promising Molecular Targets in Pharmacological Therapy for Neuronal Damage in Brain Injury.

de Los Ríos C, Viejo L, Carretero VJ, Juárez NH, Cruz-Martins N, Hernández-Guijo JM. de Los Ríos C, et al. Among authors: viejo l. Antioxidants (Basel). 2023 Jan 3;12(1):118. doi: 10.3390/antiox12010118. Antioxidants (Basel). 2023. PMID: 36670980 Free PMC article. Review.

8

Cellulose/pectin-based materials incorporating Laponite-indole derivative hybrid for oral administration and controlled delivery of the neuroprotective drug.

Bravo I, Viejo L, de Los Ríos C, García-Frutos EM, Darder M. Bravo I, et al. Among authors: viejo l. Int J Biol Macromol. 2023 Apr 15;234:123765. doi: 10.1016/j.ijbiomac.2023.123765. Epub 2023 Feb 20. Int J Biol Macromol. 2023. PMID: 36812973 Free article.

9

Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease.

Viejo L, Noori A, Merrill E, Das S, Hyman BT, Serrano-Pozo A. Viejo L, et al. Neuropathol Appl Neurobiol. 2022 Feb;48(1):e12753. doi: 10.1111/nan.12753. Epub 2021 Aug 17. Neuropathol Appl Neurobiol. 2022. PMID: 34297416 Free PMC article.

10

[Clinical value of the ankle-brachial index in patients at risk of cardiovascular disease but without known atherothrombotic disease: VITAMIN study].

Manzano L, García-Díaz Jde D, Gómez-Cerezo J, Mateos J, del Valle FJ, Medina-Asensio J, Viejo LF, Fernández-Ballesteros A, Solís J, Herrero Domingo A, Ferreira E, Sánchez-Fuentes D, Barragán JM, González-Moraleja J, Vargas JA, López-Jiménez M, Zamora J; Grupo de Estudio De la ARteriopatia Asintomatica (GEDARA). Manzano L, et al. Among authors: viejo lf. Rev Esp Cardiol. 2006 Jul;59(7):662-70. Rev Esp Cardiol. 2006. PMID: 16938208 Free article. Spanish.

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