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Page 1
Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism.
Sridhar A, Depla JA, Mulder LA, Karelehto E, Brouwer L, Kruiswijk L, Vieira de Sá R, Meijer A, Evers MM, van Kuppeveld FJM, Pajkrt D, Wolthers KC. Sridhar A, et al. Among authors: vieira de sa r. Microbiol Spectr. 2022 Oct 26;10(5):e0169422. doi: 10.1128/spectrum.01694-22. Epub 2022 Sep 26. Microbiol Spectr. 2022. PMID: 36154279 Free PMC article.
C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits.
Koppers M, Blokhuis AM, Westeneng HJ, Terpstra ML, Zundel CA, Vieira de Sá R, Schellevis RD, Waite AJ, Blake DJ, Veldink JH, van den Berg LH, Pasterkamp RJ. Koppers M, et al. Among authors: vieira de sa r. Ann Neurol. 2015 Sep;78(3):426-38. doi: 10.1002/ana.24453. Epub 2015 Jul 3. Ann Neurol. 2015. PMID: 26044557 Free PMC article.
Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA).
Rademacher S, Verheijen BM, Hensel N, Peters M, Bora G, Brandes G, Vieira de Sá R, Heidrich N, Fischer S, Brinkmann H, van der Pol WL, Wirth B, Pasterkamp RJ, Claus P. Rademacher S, et al. Among authors: vieira de sa r. Hum Mol Genet. 2017 Oct 15;26(20):3946-3959. doi: 10.1093/hmg/ddx282. Hum Mol Genet. 2017. PMID: 29016853
Microglia innately develop within cerebral organoids.
Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJ. Ormel PR, et al. Among authors: vieira de sa r. Nat Commun. 2018 Oct 9;9(1):4167. doi: 10.1038/s41467-018-06684-2. Nat Commun. 2018. PMID: 30301888 Free PMC article.
Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease.
Capendale PE, García-Rodríguez I, Ambikan AT, Mulder LA, Depla JA, Freeze E, Koen G, Calitz C, Sood V, Vieira de Sá R, Neogi U, Pajkrt D, Sridhar A, Wolthers KC. Capendale PE, et al. Among authors: vieira de sa r. Nat Commun. 2024 Mar 21;15(1):2532. doi: 10.1038/s41467-024-46634-9. Nat Commun. 2024. PMID: 38514653 Free PMC article.
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models.
García-Rodríguez I, Moreni G, Capendale PE, Mulder L, Aknouch I, Vieira de Sá R, Johannesson N, Freeze E, van Eijk H, Koen G, Wolthers KC, Pajkrt D, Sridhar A, Calitz C. García-Rodríguez I, et al. Among authors: vieira de sa r. Antiviral Res. 2024 Feb;222:105798. doi: 10.1016/j.antiviral.2024.105798. Epub 2024 Jan 6. Antiviral Res. 2024. PMID: 38190972 Free article.