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Chloroquine attenuates diet-induced obesity and glucose intolerance through a mechanism that might involve FGF-21, but not UCP-1-mediated thermogenesis and inhibition of adipocyte autophagy.
Ortiz-Silva M, Leonardi BF, Castro É, Peixoto ÁS, Gilio GR, Oliveira TE, Tomazelli CA, Andrade ML, Moreno MF, Belchior T, Magdalon J, Vieira TS, Donado-Pestana CM, Festuccia WT. Ortiz-Silva M, et al. Among authors: vieira ts. Mol Cell Endocrinol. 2023 Dec 1;578:112074. doi: 10.1016/j.mce.2023.112074. Epub 2023 Sep 22. Mol Cell Endocrinol. 2023. PMID: 37742789
Constitutive Activation of the Nutrient Sensor mTORC1 in Myeloid Cells Induced by Tsc1 Deletion Protects Mice from Diet-Induced Obesity.
Paschoal VA, Belchior T, Amano MT, Burgos-Silva M, Peixoto AS, Magdalon J, Vieira TS, Andrade ML, Moreno MF, Chimin P, Câmara NO, Festuccia WT. Paschoal VA, et al. Among authors: vieira ts. Mol Nutr Food Res. 2018 Sep;62(17):e1800283. doi: 10.1002/mnfr.201800283. Epub 2018 Aug 8. Mol Nutr Food Res. 2018. PMID: 30001482
PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.
Andrade ML, Gilio GR, Perandini LA, Peixoto AS, Moreno MF, Castro É, Oliveira TE, Vieira TS, Ortiz-Silva M, Thomazelli CA, Chaves-Filho AB, Belchior T, Chimin P, Magdalon J, Ivison R, Pant D, Tsai L, Yoshinaga MY, Miyamoto S, Festuccia WT. Andrade ML, et al. Among authors: vieira ts. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Aug;1866(8):158967. doi: 10.1016/j.bbalip.2021.158967. Epub 2021 May 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 34004356 Free PMC article.
Hepatocellular carcinoma induced by hepatocyte Pten deletion reduces BAT UCP-1 and thermogenic capacity in mice, despite increasing serum FGF-21 and iWAT browning.
Peixoto ÁS, Moreno MF, Castro É, Perandini LA, Belchior T, Oliveira TE, Vieira TS, Gilio GR, Tomazelli CA, Leonardi BF, Ortiz-Silva M, Silva Junior LP, Moretti EH, Steiner AA, Festuccia WT. Peixoto ÁS, et al. Among authors: vieira ts. J Physiol Biochem. 2023 Nov;79(4):731-743. doi: 10.1007/s13105-023-00970-4. Epub 2023 Jul 5. J Physiol Biochem. 2023. PMID: 37405670
Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.
Castro É, Vieira TS, Oliveira TE, Ortiz-Silva M, Andrade ML, Tomazelli CA, Peixoto AS, Sobrinho CR, Moreno MF, Gilio GR, Moreira RJ, Guimarães RC, Perandini LA, Chimin P, Reckziegel P, Moretti EH, Steiner AA, Laplante M, Festuccia WT. Castro É, et al. Among authors: vieira ts. Am J Physiol Endocrinol Metab. 2021 Nov 1;321(5):E592-E605. doi: 10.1152/ajpendo.00587.2020. Epub 2021 Sep 20. Am J Physiol Endocrinol Metab. 2021. PMID: 34541875 Free article.
Long-term heat acclimation training in mice: Similar metabolic and running performance adaptations despite a lower absolute intensity than training at temperate conditions.
Zanetti GO, Pessoa PWM, Vieira TS, Garcia RA, Santos Barbosa NH, Arantes RME, Kettelhut IDC, Navegantes LCC, Wanner SP, Soares DD, Gonçalves DAP. Zanetti GO, et al. Among authors: vieira ts. J Therm Biol. 2024 Jan;119:103797. doi: 10.1016/j.jtherbio.2024.103797. Epub 2024 Jan 24. J Therm Biol. 2024. PMID: 38340467
Resveratrol directly suppresses proteolysis possibly via PKA/CREB signaling in denervated rat skeletal muscle.
I S Júnior I, Zanetti GO, Vieira TS, Albuquerque FP, Gomes DA, Paula-Gomes S, Valentim RR, Graça FA, Kettlhut IC, Navegantes LCC, Gonçalves DAP, Lira EC. I S Júnior I, et al. Among authors: vieira ts. An Acad Bras Cienc. 2023 Dec 1;95(suppl 2):e20220877. doi: 10.1590/0001-3765202320220877. eCollection 2023. An Acad Bras Cienc. 2023. PMID: 38055559 Free article.
66 results