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Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Among authors: viault g. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.
Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors.
Alsabil K, Suor-Cherer S, Koeberle A, Viault G, Lavaud A, Temml V, Waltenberger B, Schuster D, Litaudon M, Lorkowski S, de Vaumas R, Helesbeux JJ, Guilet D, Stuppner H, Werz O, Seraphin D, Richomme P. Alsabil K, et al. Among authors: viault g. Planta Med. 2016 Jul;82(11-12):1110-6. doi: 10.1055/s-0042-108739. Epub 2016 Jun 10. Planta Med. 2016. PMID: 27286327
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation.
Neukirch K, Alsabil K, Dinh CP, Bilancia R, Raasch M, Ville A, Cerqua I, Viault G, Bréard D, Pace S, Temml V, Brunner E, Jordan PM, Marques MC, Loeser K, Gollowitzer A, Permann S, Gerstmeier J, Lorkowski S, Stuppner H, Garscha U, Rodrigues T, Bernardes GJL, Schuster D, Séraphin D, Richomme P, Rossi A, Mosig AS, Roviezzo F, Werz O, Helesbeux JJ, Koeberle A. Neukirch K, et al. Among authors: viault g. J Med Chem. 2021 Aug 12;64(15):11496-11526. doi: 10.1021/acs.jmedchem.1c00806. Epub 2021 Jul 19. J Med Chem. 2021. PMID: 34279935 Free PMC article.
Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages.
Kretzer C, Jordan PM, Meyer KPL, Hoff D, Werner M, Hofstetter RK, Koeberle A, Cala Peralta A, Viault G, Seraphin D, Richomme P, Helesbeux JJ, Stuppner H, Temml V, Schuster D, Werz O. Kretzer C, et al. Among authors: viault g. Biochem Pharmacol. 2022 Jan;195:114825. doi: 10.1016/j.bcp.2021.114825. Epub 2021 Nov 8. Biochem Pharmacol. 2022. PMID: 34762841
Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3.
Möller G, Temml V, Cala Peralta A, Gruet O, Richomme P, Séraphin D, Viault G, Kraus L, Huber-Cantonati P, Schopfhauser E, Pachmayr J, Tokarz J, Schuster D, Helesbeux JJ, Dyar KA. Möller G, et al. Among authors: viault g. Metabolites. 2022 Jan 21;12(2):99. doi: 10.3390/metabo12020099. Metabolites. 2022. PMID: 35208174 Free PMC article.
Natural Products Targeting the Fungal Unfolded Protein Response as an Alternative Crop Protection Strategy.
Charpentier T, Viault G, Le Ray AM, Bataillé-Simoneau N, Helesbeux JJ, Blon N, Bastide F, Marchi M, Aligon S, Bruguière A, Dinh CP, Benbelkacem Z, Dallery JF, Simoneau P, Richomme P, Guillemette T. Charpentier T, et al. Among authors: viault g. J Agric Food Chem. 2023 Sep 20;71(37):13706-13716. doi: 10.1021/acs.jafc.3c03602. Epub 2023 Sep 11. J Agric Food Chem. 2023. PMID: 37697453
17 results