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Page 1
Donated chemical probes for open science.
Müller S, Ackloo S, Arrowsmith CH, Bauser M, Baryza JL, Blagg J, Böttcher J, Bountra C, Brown PJ, Bunnage ME, Carter AJ, Damerell D, Dötsch V, Drewry DH, Edwards AM, Edwards J, Elkins JM, Fischer C, Frye SV, Gollner A, Grimshaw CE, IJzerman A, Hanke T, Hartung IV, Hitchcock S, Howe T, Hughes TV, Laufer S, Li VM, Liras S, Marsden BD, Matsui H, Mathias J, O'Hagan RC, Owen DR, Pande V, Rauh D, Rosenberg SH, Roth BL, Schneider NS, Scholten C, Singh Saikatendu K, Simeonov A, Takizawa M, Tse C, Thompson PR, Treiber DK, Viana AY, Wells CI, Willson TM, Zuercher WJ, Knapp S, Mueller-Fahrnow A. Müller S, et al. Among authors: viana ay. Elife. 2018 Apr 20;7:e34311. doi: 10.7554/eLife.34311. Elife. 2018. PMID: 29676732 Free PMC article.
Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet.
Kushiyama A, Shojima N, Ogihara T, Inukai K, Sakoda H, Fujishiro M, Fukushima Y, Anai M, Ono H, Horike N, Viana AY, Uchijima Y, Nishiyama K, Shimosawa T, Fujita T, Katagiri H, Oka Y, Kurihara H, Asano T. Kushiyama A, et al. Among authors: viana ay. J Biol Chem. 2005 Dec 23;280(51):42016-25. doi: 10.1074/jbc.M503065200. Epub 2005 Oct 21. J Biol Chem. 2005. PMID: 16243841 Free article.
Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity.
Sakoda H, Fujishiro M, Fujio J, Shojima N, Ogihara T, Kushiyama A, Fukushima Y, Anai M, Ono H, Kikuchi M, Horike N, Viana AY, Uchijima Y, Kurihara H, Asano T. Sakoda H, et al. Among authors: viana ay. Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E474-81. doi: 10.1152/ajpendo.00003.2005. Epub 2005 May 10. Am J Physiol Endocrinol Metab. 2005. PMID: 15886229 Free article.
Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow.
Shojima N, Ogihara T, Inukai K, Fujishiro M, Sakoda H, Kushiyama A, Katagiri H, Anai M, Ono H, Fukushima Y, Horike N, Viana AY, Uchijima Y, Kurihara H, Asano T. Shojima N, et al. Among authors: viana ay. Diabetologia. 2005 May;48(5):984-92. doi: 10.1007/s00125-005-1735-1. Epub 2005 Apr 15. Diabetologia. 2005. PMID: 15834545
Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement.
Ono H, Shimano H, Katagiri H, Yahagi N, Sakoda H, Onishi Y, Anai M, Ogihara T, Fujishiro M, Viana AY, Fukushima Y, Abe M, Shojima N, Kikuchi M, Yamada N, Oka Y, Asano T. Ono H, et al. Among authors: viana ay. Diabetes. 2003 Dec;52(12):2905-13. doi: 10.2337/diabetes.52.12.2905. Diabetes. 2003. PMID: 14633850