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Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus.
Hasni SA, Gupta S, Davis M, Poncio E, Temesgen-Oyelakin Y, Carlucci PM, Wang X, Naqi M, Playford MP, Goel RR, Li X, Biehl AJ, Ochoa-Navas I, Manna Z, Shi Y, Thomas D, Chen J, Biancotto A, Apps R, Cheung F, Kotliarov Y, Babyak AL, Zhou H, Shi R, Stagliano K, Tsai WL, Vian L, Gazaniga N, Giudice V, Lu S, Brooks SR, MacKay M, Gregersen P, Mehta NN, Remaley AT, Diamond B, O'Shea JJ, Gadina M, Kaplan MJ. Hasni SA, et al. Among authors: vian l. Nat Commun. 2021 Jun 7;12(1):3391. doi: 10.1038/s41467-021-23361-z. Nat Commun. 2021. PMID: 34099646 Free PMC article. Clinical Trial.
JAK Inhibition Differentially Affects NK Cell and ILC1 Homeostasis.
Vian L, Le MT, Gazaniga N, Kieltyka J, Liu C, Pietropaolo G, Dell'Orso S, Brooks SR, Furumoto Y, Thomas CJ, O'Shea JJ, Sciumè G, Gadina M. Vian L, et al. Front Immunol. 2019 Dec 19;10:2972. doi: 10.3389/fimmu.2019.02972. eCollection 2019. Front Immunol. 2019. PMID: 31921209 Free PMC article.
Janus kinase (JAK) inhibition with baricitinib in refractory juvenile dermatomyositis.
Kim H, Dill S, O'Brien M, Vian L, Li X, Manukyan M, Jain M, Adeojo LW, George J, Perez M, Grom AA, Sutter M, Feldman BM, Yao L, Millwood M, Brundidge A, Pichard DC, Cowen EW, Shi Y, Lu S, Tsai WL, Gadina M, Rider LG, Colbert RA. Kim H, et al. Among authors: vian l. Ann Rheum Dis. 2021 Mar;80(3):406-408. doi: 10.1136/annrheumdis-2020-218690. Epub 2020 Aug 25. Ann Rheum Dis. 2021. PMID: 32843325 Free PMC article. No abstract available.
Type 2 immunity in the skin and lungs.
Akdis CA, Arkwright PD, Brüggen MC, Busse W, Gadina M, Guttman-Yassky E, Kabashima K, Mitamura Y, Vian L, Wu J, Palomares O. Akdis CA, et al. Among authors: vian l. Allergy. 2020 Jul;75(7):1582-1605. doi: 10.1111/all.14318. Epub 2020 May 10. Allergy. 2020. PMID: 32319104 Review.
Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver.
Di Censo C, Marotel M, Mattiola I, Müller L, Scarno G, Pietropaolo G, Peruzzi G, Laffranchi M, Mazej J, Hasim MS, Asif S, Russo E, Tomaipitinca L, Stabile H, Lee SH, Vian L, Gadina M, Gismondi A, Shih HY, Mikami Y, Capuano C, Bernardini G, Bonelli M, Sozzani S, Diefenbach A, Ardolino M, Santoni A, Sciumè G. Di Censo C, et al. Among authors: vian l. Eur J Immunol. 2021 Nov;51(11):2568-2575. doi: 10.1002/eji.202149209. Epub 2021 Aug 19. Eur J Immunol. 2021. PMID: 34347289 Free PMC article.
A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans.
Tsai PF, Dell'Orso S, Rodriguez J, Vivanco KO, Ko KD, Jiang K, Juan AH, Sarshad AA, Vian L, Tran M, Wangsa D, Wang AH, Perovanovic J, Anastasakis D, Ralston E, Ried T, Sun HW, Hafner M, Larson DR, Sartorelli V. Tsai PF, et al. Among authors: vian l. Mol Cell. 2018 Jul 5;71(1):129-141.e8. doi: 10.1016/j.molcel.2018.06.008. Mol Cell. 2018. PMID: 29979962 Free PMC article.
60 results