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CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection.
Foreman TW, Nelson CE, Kauffman KD, Lora NE, Vinhaes CL, Dorosky DE, Sakai S, Gomez F, Fleegle JD, Parham M, Perera SR, Lindestam Arlehamn CS, Sette A; Tuberculosis Imaging Program; Brenchley JM, Queiroz ATL, Andrade BB, Kabat J, Via LE, Barber DL. Foreman TW, et al. Among authors: via le. Cell Rep. 2022 May 31;39(9):110896. doi: 10.1016/j.celrep.2022.110896. Cell Rep. 2022. PMID: 35649361 Free article.
Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.
Mayer-Barber KD, Andrade BB, Oland SD, Amaral EP, Barber DL, Gonzales J, Derrick SC, Shi R, Kumar NP, Wei W, Yuan X, Zhang G, Cai Y, Babu S, Catalfamo M, Salazar AM, Via LE, Barry CE 3rd, Sher A. Mayer-Barber KD, et al. Among authors: via le. Nature. 2014 Jul 3;511(7507):99-103. doi: 10.1038/nature13489. Epub 2014 Jun 25. Nature. 2014. PMID: 24990750 Free PMC article.
Mathematical Model of Oxygen Transport in Tuberculosis Granulomas.
Datta M, Via LE, Chen W, Baish JW, Xu L, Barry CE 3rd, Jain RK. Datta M, et al. Among authors: via le. Ann Biomed Eng. 2016 Apr;44(4):863-72. doi: 10.1007/s10439-015-1415-3. Epub 2015 Aug 8. Ann Biomed Eng. 2016. PMID: 26253038 Free PMC article.
Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques.
Kauffman KD, Sallin MA, Sakai S, Kamenyeva O, Kabat J, Weiner D, Sutphin M, Schimel D, Via L, Barry CE 3rd, Wilder-Kofie T, Moore I, Moore R, Barber DL. Kauffman KD, et al. Mucosal Immunol. 2018 Mar;11(2):462-473. doi: 10.1038/mi.2017.60. Epub 2017 Jul 26. Mucosal Immunol. 2018. PMID: 28745326 Free PMC article.
Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations.
Oliveira-de-Souza D, Vinhaes CL, Arriaga MB, Kumar NP, Cubillos-Angulo JM, Shi R, Wei W, Yuan X, Zhang G, Cai Y, Barry CE 3rd, Via LE, Sher A, Babu S, Mayer-Barber KD, Nakaya HI, Fukutani KF, Andrade BB. Oliveira-de-Souza D, et al. Among authors: via le. Sci Rep. 2019 May 29;9(1):8002. doi: 10.1038/s41598-019-44513-8. Sci Rep. 2019. PMID: 31142816 Free PMC article.
Changes in inflammatory protein and lipid mediator profiles persist after antitubercular treatment of pulmonary and extrapulmonary tuberculosis: A prospective cohort study.
Vinhaes CL, Oliveira-de-Souza D, Silveira-Mattos PS, Nogueira B, Shi R, Wei W, Yuan X, Zhang G, Cai Y, Barry CE 3rd, Via LE, Fukutani KF, Andrade BB, Mayer-Barber KD. Vinhaes CL, et al. Among authors: via le. Cytokine. 2019 Nov;123:154759. doi: 10.1016/j.cyto.2019.154759. Epub 2019 Jun 18. Cytokine. 2019. PMID: 31226436 Free PMC article. Clinical Trial.
PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques.
Kauffman KD, Sakai S, Lora NE, Namasivayam S, Baker PJ, Kamenyeva O, Foreman TW, Nelson CE, Oliveira-de-Souza D, Vinhaes CL, Yaniv Z, Lindestam Arleham CS, Sette A, Freeman GJ, Moore R; NIAID/DIR Tuberculosis Imaging Program; Sher A, Mayer-Barber KD, Andrade BB, Kabat J, Via LE, Barber DL. Kauffman KD, et al. Among authors: via le. Sci Immunol. 2021 Jan 15;6(55):eabf3861. doi: 10.1126/sciimmunol.abf3861. Sci Immunol. 2021. PMID: 33452107 Free PMC article.
Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates.
Sakai S, Lora NE, Kauffman KD, Dorosky DE, Oh S, Namasivayam S, Gomez F, Fleegle JD; Tuberculosis Imaging Program; Arlehamn CSL, Sette A, Sher A, Freeman GJ, Via LE, Barry Iii CE, Barber DL. Sakai S, et al. Among authors: via le. Mucosal Immunol. 2021 Sep;14(5):1055-1066. doi: 10.1038/s41385-021-00425-3. Epub 2021 Jun 22. Mucosal Immunol. 2021. PMID: 34158594 Free PMC article.
Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice.
Bohrer AC, Castro E, Hu Z, Queiroz ATL, Tocheny CE, Assmann M, Sakai S, Nelson C, Baker PJ, Ma H, Wang L, Zilu W, du Bruyn E, Riou C, Kauffman KD; Tuberculosis Imaging Program; Moore IN, Del Nonno F, Petrone L, Goletti D, Martineau AR, Lowe DM, Cronan MR, Wilkinson RJ, Barry CE, Via LE, Barber DL, Klion AD, Andrade BB, Song Y, Wong KW, Mayer-Barber KD. Bohrer AC, et al. Among authors: via le. J Exp Med. 2021 Oct 4;218(10):e20210469. doi: 10.1084/jem.20210469. Epub 2021 Aug 4. J Exp Med. 2021. PMID: 34347010 Free PMC article.
Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues.
Nelson CE, Namasivayam S, Foreman TW, Kauffman KD, Sakai S, Dorosky DE, Lora NE; NIAID/DIR Tuberculosis Imaging Program; Brooks K, Potter EL, Garza NL, Lafont BAP, Johnson RF, Roederer M, Sher A, Weiskopf D, Sette A, de Wit E, Hickman HD, Brenchley JM, Via LE, Barber DL. Nelson CE, et al. Among authors: via le. Sci Immunol. 2022 Mar 10:eabo0535. doi: 10.1126/sciimmunol.abo0535. Online ahead of print. Sci Immunol. 2022. PMID: 35271298 Free PMC article.
149 results