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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models.
Ren F, Aliper A, Chen J, Zhao H, Rao S, Kuppe C, Ozerov IV, Zhang M, Witte K, Kruse C, Aladinskiy V, Ivanenkov Y, Polykovskiy D, Fu Y, Babin E, Qiao J, Liang X, Mou Z, Wang H, Pun FW, Ayuso PT, Veviorskiy A, Song D, Liu S, Zhang B, Naumov V, Ding X, Kukharenko A, Izumchenko E, Zhavoronkov A. Ren F, et al. Among authors: veviorskiy a. Nat Biotechnol. 2024 Mar 8. doi: 10.1038/s41587-024-02143-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 38459338
Defining the progeria phenome.
Worm C, Schambye MER, Mkrtchyan GV, Veviorskiy A, Shneyderman A, Ozerov IV, Zhavoronkov A, Bakula D, Scheibye-Knudsen M. Worm C, et al. Among authors: veviorskiy a. Aging (Albany NY). 2024 Feb 9;16(3):2026-2046. doi: 10.18632/aging.205537. Epub 2024 Feb 9. Aging (Albany NY). 2024. PMID: 38345566 Free PMC article.
Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform.
Olsen A, Harpaz Z, Ren C, Shneyderman A, Veviorskiy A, Dralkina M, Konnov S, Shcheglova O, Pun FW, Leung GHD, Leung HW, Ozerov IV, Aliper A, Korzinkin M, Zhavoronkov A. Olsen A, et al. Among authors: veviorskiy a. Aging (Albany NY). 2023 Apr 26;15(8):2863-2876. doi: 10.18632/aging.204678. Epub 2023 Apr 26. Aging (Albany NY). 2023. PMID: 37100462 Free PMC article.