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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.
Dawson A, Zarou MM, Prasad B, Bittencourt-Silvestre J, Zerbst D, Himonas E, Hsieh YC, van Loon I, Blanco GR, Ianniciello A, Kerekes Z, Krishnan V, Agarwal P, Almasoudi H, McCluskey L, Hopcroft LEM, Scott MT, Baquero P, Dunn K, Vetrie D, Copland M, Bhatia R, Coffelt SB, Tiong OS, Wheadon H, Zanivan S, Kirschner K, Helgason GV. Dawson A, et al. Among authors: vetrie d. Nat Commun. 2024 Feb 5;15(1):1090. doi: 10.1038/s41467-024-45471-0. Nat Commun. 2024. PMID: 38316788 Free PMC article.
Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells.
Abraham SA, Hopcroft LE, Carrick E, Drotar ME, Dunn K, Williamson AJ, Korfi K, Baquero P, Park LE, Scott MT, Pellicano F, Pierce A, Copland M, Nourse C, Grimmond SM, Vetrie D, Whetton AD, Holyoake TL. Abraham SA, et al. Among authors: vetrie d. Nature. 2016 Jun 16;534(7607):341-6. doi: 10.1038/nature18288. Epub 2016 Jun 8. Nature. 2016. PMID: 27281222 Free PMC article.
ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Ianniciello A, Zarou MM, Rattigan KM, Scott M, Dawson A, Dunn K, Brabcova Z, Kalkman ER, Nixon C, Michie AM, Copland M, Vetrie D, Ambler M, Saxty B, Helgason GV. Ianniciello A, et al. Among authors: vetrie d. Sci Transl Med. 2021 Sep 29;13(613):eabd5016. doi: 10.1126/scitranslmed.abd5016. Epub 2021 Sep 29. Sci Transl Med. 2021. PMID: 34586834 Free PMC article.
Epigenetic Reprogramming and Emerging Epigenetic Therapies in CML.
Bugler J, Kinstrie R, Scott MT, Vetrie D. Bugler J, et al. Among authors: vetrie d. Front Cell Dev Biol. 2019 Jul 17;7:136. doi: 10.3389/fcell.2019.00136. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31380371 Free PMC article. Review.
Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition.
Scott MT, Korfi K, Saffrey P, Hopcroft LE, Kinstrie R, Pellicano F, Guenther C, Gallipoli P, Cruz M, Dunn K, Jorgensen HG, Cassels JE, Hamilton A, Crossan A, Sinclair A, Holyoake TL, Vetrie D. Scott MT, et al. Among authors: vetrie d. Cancer Discov. 2016 Nov;6(11):1248-1257. doi: 10.1158/2159-8290.CD-16-0263. Epub 2016 Sep 14. Cancer Discov. 2016. PMID: 27630125 Free PMC article.
The Spliceosome: A New Therapeutic Target in Chronic Myeloid Leukaemia.
Lebecque B, Bourgne C, Munje C, Berger J, Tassin T, Cony-Makhoul P, Guerci-Bresler A, Johnson-Ansah H, Liu W, Saugues S, Tchirkov A, Vetrie D, Copland M, Berger MG. Lebecque B, et al. Among authors: vetrie d. Cancers (Basel). 2022 Sep 27;14(19):4695. doi: 10.3390/cancers14194695. Cancers (Basel). 2022. PMID: 36230624 Free PMC article.
Cancer: Repositioned to kill stem cells.
Holyoake T, Vetrie D. Holyoake T, et al. Among authors: vetrie d. Nature. 2015 Sep 17;525(7569):328-9. doi: 10.1038/nature15213. Epub 2015 Sep 2. Nature. 2015. PMID: 26331538 No abstract available.
66 results