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A reference human induced pluripotent stem cell line for large-scale collaborative studies.
Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, Santiana M, Faghri F, Nalls MA, Vitale D, Ballard S, Qi YA, Ramos DM, Anderson KM, Stadler J, Narayan P, Papademetriou J, Reilly L, Nelson MP, Aggarwal S, Rosen LU, Kirwan P, Pisupati V, Coon SL, Scholz SW, Priebe T, Öttl M, Dong J, Meijer M, Janssen LJM, Lourenco VS, van der Kant R, Crusius D, Paquet D, Raulin AC, Bu G, Held A, Wainger BJ, Gabriele RMC, Casey JM, Wray S, Abu-Bonsrah D, Parish CL, Beccari MS, Cleveland DW, Li E, Rose IVL, Kampmann M, Calatayud Aristoy C, Verstreken P, Heinrich L, Chen MY, Schüle B, Dou D, Holzbaur ELF, Zanellati MC, Basundra R, Deshmukh M, Cohen S, Khanna R, Raman M, Nevin ZS, Matia M, Van Lent J, Timmerman V, Conklin BR, Johnson Chase K, Zhang K, Funes S, Bosco DA, Erlebach L, Welzer M, Kronenberg-Versteeg D, Lyu G, Arenas E, Coccia E, Sarrafha L, Ahfeldt T, Marioni JC, Skarnes WC, Cookson MR, Ward ME, Merkle FT. Pantazis CB, et al. Among authors: verstreken p. Cell Stem Cell. 2022 Dec 1;29(12):1685-1702.e22. doi: 10.1016/j.stem.2022.11.004. Cell Stem Cell. 2022. PMID: 36459969 Free PMC article.
Neurodegeneration cell per cell.
Balusu S, Praschberger R, Lauwers E, De Strooper B, Verstreken P. Balusu S, et al. Among authors: verstreken p. Neuron. 2023 Mar 15;111(6):767-786. doi: 10.1016/j.neuron.2023.01.016. Epub 2023 Feb 13. Neuron. 2023. PMID: 36787752 Free article. Review.
Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling.
Ermanoska B, Asselbergh B, Morant L, Petrovic-Erfurth ML, Hosseinibarkooie S, Leitão-Gonçalves R, Almeida-Souza L, Bervoets S, Sun L, Lee L, Atkinson D, Khanghahi A, Tournev I, Callaerts P, Verstreken P, Yang XL, Wirth B, Rodal AA, Timmerman V, Goode BL, Godenschwege TA, Jordanova A. Ermanoska B, et al. Among authors: verstreken p. Nat Commun. 2023 Mar 8;14(1):999. doi: 10.1038/s41467-023-35908-3. Nat Commun. 2023. PMID: 36890170 Free PMC article.
Nano-positioning and tubulin conformation contribute to axonal transport regulation of mitochondria along microtubules.
Van Steenbergen V, Lavoie-Cardinal F, Kazwiny Y, Decet M, Martens T, Verstreken P, Boesmans W, De Koninck P, Vanden Berghe P. Van Steenbergen V, et al. Among authors: verstreken p. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2203499119. doi: 10.1073/pnas.2203499119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322761 Free PMC article.
Elevated α-synuclein levels inhibit mitophagic flux.
Kinnart I, Manders L, Heyninck T, Imberechts D, Praschberger R, Schoovaerts N, Verfaillie C, Verstreken P, Vandenberghe W. Kinnart I, et al. Among authors: verstreken p. NPJ Parkinsons Dis. 2024 Apr 9;10(1):80. doi: 10.1038/s41531-024-00696-0. NPJ Parkinsons Dis. 2024. PMID: 38594264 Free PMC article.
Neuronal identity defines α-synuclein and tau toxicity.
Praschberger R, Kuenen S, Schoovaerts N, Kaempf N, Singh J, Janssens J, Swerts J, Nachman E, Calatayud C, Aerts S, Poovathingal S, Verstreken P. Praschberger R, et al. Among authors: verstreken p. Neuron. 2023 May 17;111(10):1577-1590.e11. doi: 10.1016/j.neuron.2023.02.033. Epub 2023 Mar 21. Neuron. 2023. PMID: 36948206 Free PMC article.
EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation.
Bademosi AT, Decet M, Kuenen S, Calatayud C, Swerts J, Gallego SF, Schoovaerts N, Karamanou S, Louros N, Martin E, Sibarita JB, Vints K, Gounko NV, Meunier FA, Economou A, Versées W, Rousseau F, Schymkowitz J, Soukup SF, Verstreken P. Bademosi AT, et al. Among authors: verstreken p. Neuron. 2023 May 3;111(9):1402-1422.e13. doi: 10.1016/j.neuron.2023.02.001. Epub 2023 Feb 23. Neuron. 2023. PMID: 36827984 Free PMC article.
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects.
Lambert E, Saha O, Soares Landeira B, Melo de Farias AR, Hermant X, Carrier A, Pelletier A, Gadaut J, Davoine L, Dupont C, Amouyel P, Bonnefond A, Lafont F, Abdelfettah F, Verstreken P, Chapuis J, Barois N, Delahaye F, Dermaut B, Lambert JC, Costa MR, Dourlen P. Lambert E, et al. Among authors: verstreken p. Acta Neuropathol Commun. 2022 Jan 8;10(1):4. doi: 10.1186/s40478-021-01285-5. Acta Neuropathol Commun. 2022. PMID: 34998435 Free PMC article.
133 results