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Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarró LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M. Broutier L, et al. Among authors: verstegen mm. Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13. Nat Med. 2017. PMID: 29131160 Free PMC article.
Mobilization of hepatic mesenchymal stem cells from human liver grafts.
Pan Q, Fouraschen SM, Kaya FS, Verstegen MM, Pescatori M, Stubbs AP, van Ijcken W, van der Sloot A, Smits R, Kwekkeboom J, Metselaar HJ, Kazemier G, de Jonge J, Tilanus HW, Wagemaker G, Janssen HL, van der Laan LJ. Pan Q, et al. Among authors: verstegen mm. Liver Transpl. 2011 May;17(5):596-609. doi: 10.1002/lt.22260. Liver Transpl. 2011. PMID: 21506248 Free article.
No evidence for circulating mesenchymal stem cells in patients with organ injury.
Hoogduijn MJ, Verstegen MM, Engela AU, Korevaar SS, Roemeling-van Rhijn M, Merino A, Franquesa M, de Jonge J, Ijzermans JN, Weimar W, Betjes MG, Baan CC, van der Laan LJ. Hoogduijn MJ, et al. Among authors: verstegen mm. Stem Cells Dev. 2014 Oct 1;23(19):2328-35. doi: 10.1089/scd.2014.0269. Epub 2014 Aug 25. Stem Cells Dev. 2014. PMID: 25105211
Long-term culture of genome-stable bipotent stem cells from adult human liver.
Huch M, Gehart H, van Boxtel R, Hamer K, Blokzijl F, Verstegen MM, Ellis E, van Wenum M, Fuchs SA, de Ligt J, van de Wetering M, Sasaki N, Boers SJ, Kemperman H, de Jonge J, Ijzermans JN, Nieuwenhuis EE, Hoekstra R, Strom S, Vries RR, van der Laan LJ, Cuppen E, Clevers H. Huch M, et al. Among authors: verstegen mm. Cell. 2015 Jan 15;160(1-2):299-312. doi: 10.1016/j.cell.2014.11.050. Epub 2014 Dec 18. Cell. 2015. PMID: 25533785 Free PMC article.
Human graft-derived mesenchymal stromal cells potently suppress alloreactive T-cell responses.
de Mare-Bredemeijer EL, Mancham S, Verstegen MM, de Ruiter PE, van Gent R, O'Neill D, Tilanus HW, Metselaar HJ, de Jonge J, Kwekkeboom J, Hall SR, van der Laan LJ. de Mare-Bredemeijer EL, et al. Among authors: verstegen mm. Stem Cells Dev. 2015 Jun 15;24(12):1436-47. doi: 10.1089/scd.2014.0485. Epub 2015 Apr 28. Stem Cells Dev. 2015. PMID: 25744002
Gene therapies for hepatitis C virus.
Verstegen MM, Pan Q, van der Laan LJ. Verstegen MM, et al. Adv Exp Med Biol. 2015;848:1-29. doi: 10.1007/978-1-4939-2432-5_1. Adv Exp Med Biol. 2015. PMID: 25757613 Review.
Mesenchymal Stromal Cell-Derived Factors Promote Tissue Repair in a Small-for-Size Ischemic Liver Model but Do Not Protect against Early Effects of Ischemia and Reperfusion Injury.
Fouraschen SM, Wolf JH, van der Laan LJ, de Ruiter PE, Hancock WW, van Kooten JP, Verstegen MM, Olthoff KM, de Jonge J. Fouraschen SM, et al. Among authors: verstegen mm. J Immunol Res. 2015;2015:202975. doi: 10.1155/2015/202975. Epub 2015 Aug 24. J Immunol Res. 2015. PMID: 26380314 Free PMC article.
Tissue-specific mutation accumulation in human adult stem cells during life.
Blokzijl F, de Ligt J, Jager M, Sasselli V, Roerink S, Sasaki N, Huch M, Boymans S, Kuijk E, Prins P, Nijman IJ, Martincorena I, Mokry M, Wiegerinck CL, Middendorp S, Sato T, Schwank G, Nieuwenhuis EE, Verstegen MM, van der Laan LJ, de Jonge J, IJzermans JN, Vries RG, van de Wetering M, Stratton MR, Clevers H, Cuppen E, van Boxtel R. Blokzijl F, et al. Among authors: verstegen mm. Nature. 2016 Oct 13;538(7624):260-264. doi: 10.1038/nature19768. Epub 2016 Oct 3. Nature. 2016. PMID: 27698416 Free PMC article.
Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells.
Tüysüz N, van Bloois L, van den Brink S, Begthel H, Verstegen MM, Cruz LJ, Hui L, van der Laan LJ, de Jonge J, Vries R, Braakman E, Mastrobattista E, Cornelissen JJ, Clevers H, Ten Berge D. Tüysüz N, et al. Among authors: verstegen mm. Nat Commun. 2017 Mar 6;8:14578. doi: 10.1038/ncomms14578. Nat Commun. 2017. PMID: 28262686 Free PMC article.
87 results