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Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, Ito H, Hammoudeh M, Emadi SA, Masri BK, Halabi H, Badsha H, Uthman IW, Wu X, Lin L, Li T, Plant D, Barton A, Orozco G, Verstappen SMM, Bowes J, MacGregor AJ, Honda S, Koido M, Tomizuka K, Kamatani Y, Tanaka H, Tanaka E, Suzuki A, Maeda Y, Yamamoto K, Miyawaki S, Xie G, Zhang J, Amos CI, Keystone E, Wolbink G, van der Horst-Bruinsma I, Cui J, Liao KP, Carroll RJ, Lee HS, Bang SY, Siminovitch KA, de Vries N, Alfredsson L, Rantapää-Dahlqvist S, Karlson EW, Bae SC, Kimberly RP, Edberg JC, Mariette X, Huizinga T, Dieudé P, Schneider M, Kerick M, Denny JC; BioBank Japan Project; Matsuda K, Matsuo K, Mimori T, Matsuda F, Fujio K, Tanaka Y, Kumanogoh A, Traylor M, Lewis CM, Eyre S, Xu H, Saxena R, Arayssi T, Kochi Y, Ikari K, Harigai M, Gregersen PK, Yamamoto K, Louis Bridges S Jr, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S. Ishigaki K, et al. Among authors: verstappen smm. Nat Genet. 2022 Nov;54(11):1640-1651. doi: 10.1038/s41588-022-01213-w. Epub 2022 Nov 4. Nat Genet. 2022. PMID: 36333501 Free PMC article.
Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.
van Wesemael TJ, Ajeganova S, Humphreys J, Terao C, Muhammad A, Symmons DP, MacGregor AJ, Hafström I, Trouw LA, van der Helm-van Mil AH, Huizinga TW, Mimori T, Toes RE, Matsuda F, Svensson B, Verstappen SM, van der Woude D. van Wesemael TJ, et al. Arthritis Res Ther. 2016 Dec 1;18(1):285. doi: 10.1186/s13075-016-1177-9. Arthritis Res Ther. 2016. PMID: 27906045 Free PMC article.
Twenty-Year Outcome and Association Between Early Treatment and Mortality and Disability in an Inception Cohort of Patients With Rheumatoid Arthritis: Results From the Norfolk Arthritis Register.
Gwinnutt JM, Symmons DPM, MacGregor AJ, Chipping JR, Marshall T, Lunt M, Verstappen SMM. Gwinnutt JM, et al. Among authors: verstappen smm. Arthritis Rheumatol. 2017 Aug;69(8):1566-1575. doi: 10.1002/art.40090. Epub 2017 Jul 10. Arthritis Rheumatol. 2017. PMID: 28425173 Free PMC article.
HLA-A 31:01 is not associated with the development of methotrexate pneumonitis in the UK population: results from a genome-wide association study.
Bluett J, Owen SA, Massey J, Alfirevic A, Pirmohamed M, Plant D, Verstappen SMM, Barton A; Pneumonitis Study Consortium. Bluett J, et al. Among authors: verstappen smm. Ann Rheum Dis. 2017 Dec;76(12):e51. doi: 10.1136/annrheumdis-2017-211512. Epub 2017 May 12. Ann Rheum Dis. 2017. PMID: 28500057 No abstract available.
Have the 10-year outcomes of patients with early inflammatory arthritis improved in the new millennium compared with the decade before? Results from the Norfolk Arthritis Register.
Gwinnutt JM, Symmons DPM, MacGregor AJ, Chipping JR, Marshall T, Lunt M, Verstappen SMM. Gwinnutt JM, et al. Among authors: verstappen smm. Ann Rheum Dis. 2018 Jun;77(6):848-854. doi: 10.1136/annrheumdis-2017-212426. Epub 2018 Feb 23. Ann Rheum Dis. 2018. PMID: 29475855 Free PMC article.
Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.
Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M, Plant D, Colombo M, Orchard P, Twigg S, McInnes IB, Porter D, Freeston JE, Nam JL, Cordell HJ, Isaacs JD, Strathdee JL, Arnett D, de Hair MJH, Tak PP, Aslibekyan S, van Vollenhoven RF, Padyukov L, Bridges SL, Pitzalis C, Cope AP, Verstappen SMM, Emery P, Barnes MR, Agakov F, McKeigue P, Mushiroda T, Kubo M, Weinshilboum R, Barton A, Morgan AW, Barrett JH; MATURA; and PAMERA; Consortia. Taylor JC, et al. Among authors: verstappen smm. Pharmacogenomics J. 2018 Jul;18(4):528-538. doi: 10.1038/s41397-018-0025-5. Epub 2018 May 25. Pharmacogenomics J. 2018. PMID: 29795407 Free article. Review.
The prevalence of co-morbidities and their impact on physical activity in people with inflammatory rheumatic diseases compared with the general population: results from the UK Biobank.
Cook MJ, Bellou E, Bowes J, Sergeant JC, O'Neill TW, Barton A, Verstappen SMM. Cook MJ, et al. Among authors: verstappen smm. Rheumatology (Oxford). 2018 Dec 1;57(12):2172-2182. doi: 10.1093/rheumatology/key224. Rheumatology (Oxford). 2018. PMID: 30107595 Free PMC article.
Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis.
Hensor EMA, McKeigue P, Ling SF, Colombo M, Barrett JH, Nam JL, Freeston J, Buch MH, Spiliopoulou A, Agakov F, Kelly S, Lewis MJ, Verstappen SMM, MacGregor AJ, Viatte S, Barton A, Pitzalis C, Emery P, Conaghan PG, Morgan AW. Hensor EMA, et al. Among authors: verstappen smm. Rheumatology (Oxford). 2019 Mar 1;58(8):1400-9. doi: 10.1093/rheumatology/kez049. Online ahead of print. Rheumatology (Oxford). 2019. PMID: 30824919 Free PMC article.
167 results