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Design of protein-binding proteins from the target structure alone.
Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Cao L, et al. Among authors: verschueren khg. Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24. Nature. 2022. PMID: 35332283 Free PMC article.
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Persson EK, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier JM, Deswarte K, Verschueren KHG, Dansercoer A, Gras D, Chanez P, Bachert C, Gonçalves A, Van Gorp H, De Haard H, Blanchetot C, Saunders M, Hammad H, Savvides SN, Lambrecht BN. Persson EK, et al. Among authors: verschueren khg. Science. 2019 May 24;364(6442):eaaw4295. doi: 10.1126/science.aaw4295. Science. 2019. PMID: 31123109
Structure and dynamics of SARS coronavirus main proteinase (Mpro).
Hilgenfeld R, Anand K, Mesters JR, Rao Z, Shen X, Jiang H, Tan J, Verschueren KH. Hilgenfeld R, et al. Adv Exp Med Biol. 2006;581:585-91. doi: 10.1007/978-0-387-33012-9_106. Adv Exp Med Biol. 2006. PMID: 17037602 Free PMC article. No abstract available.
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.
De Genst EJ, Guilliams T, Wellens J, O'Day EM, Waudby CA, Meehan S, Dumoulin M, Hsu ST, Cremades N, Verschueren KH, Pardon E, Wyns L, Steyaert J, Christodoulou J, Dobson CM. De Genst EJ, et al. J Mol Biol. 2010 Sep 17;402(2):326-43. doi: 10.1016/j.jmb.2010.07.001. Epub 2010 Jul 8. J Mol Biol. 2010. PMID: 20620148 Free article.
20 results