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Page 1
Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15.
Ng M, Verboon L, Issa H, Bhayadia R, Vermunt MW, Winkler R, Schüler L, Alejo O, Schuschel K, Regenyi E, Borchert D, Heuser M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Ng M, et al. Among authors: vermunt mw. iScience. 2023 Sep 7;26(10):107844. doi: 10.1016/j.isci.2023.107844. eCollection 2023 Oct 20. iScience. 2023. PMID: 37766974 Free PMC article.
Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma.
Sroka MW, Skopelitis D, Vermunt MW, Preall JB, El Demerdash O, de Almeida LMN, Chang K, Utama R, Gryder B, Caligiuri G, Ren D, Nalbant B, Milazzo JP, Tuveson DA, Dobin A, Hiebert SW, Stengel KR, Mantovani R, Khan J, Kohli RM, Shi J, Blobel GA, Vakoc CR. Sroka MW, et al. Among authors: vermunt mw. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2303859120. doi: 10.1073/pnas.2303859120. Epub 2023 Aug 28. Proc Natl Acad Sci U S A. 2023. PMID: 37639593 Free PMC article.
Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.
Xiang G, He X, Giardine BM, Isaac KJ, Taylor DJ, McCoy RC, Jansen C, Keller CA, Wixom AQ, Cockburn A, Miller A, Qi Q, He Y, Li Y, Lichtenberg J, Heuston EF, Anderson SM, Luan J, Vermunt MW, Yue F, Sauria MEG, Schatz MC, Taylor J, Göttgens B, Hughes JR, Higgs DR, Weiss MJ, Cheng Y, Blobel GA, Bodine DM, Zhang Y, Li Q, Mahony S, Hardison RC. Xiang G, et al. Among authors: vermunt mw. bioRxiv [Preprint]. 2024 Mar 29:2023.04.02.535219. doi: 10.1101/2023.04.02.535219. bioRxiv. 2024. PMID: 37066352 Free PMC article. Preprint.
Gene silencing dynamics are modulated by transiently active regulatory elements.
Vermunt MW, Luan J, Zhang Z, Thrasher AJ, Huang A, Saari MS, Khandros E, Beagrie RA, Zhang S, Vemulamada P, Brilleman M, Lee K, Yano JA, Giardine BM, Keller CA, Hardison RC, Blobel GA. Vermunt MW, et al. Mol Cell. 2023 Mar 2;83(5):715-730.e6. doi: 10.1016/j.molcel.2023.02.006. Mol Cell. 2023. PMID: 36868189 Free PMC article.
CTCF blocks antisense transcription initiation at divergent promoters.
Luan J, Vermunt MW, Syrett CM, Coté A, Tome JM, Zhang H, Huang A, Luppino JM, Keller CA, Giardine BM, Zhang S, Dunagin MC, Zhang Z, Joyce EF, Lis JT, Raj A, Hardison RC, Blobel GA. Luan J, et al. Among authors: vermunt mw. Nat Struct Mol Biol. 2022 Nov;29(11):1136-1144. doi: 10.1038/s41594-022-00855-y. Epub 2022 Nov 11. Nat Struct Mol Biol. 2022. PMID: 36369346 Free PMC article.
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function.
Dierickx P, Zhu K, Carpenter BJ, Jiang C, Vermunt MW, Xiao Y, Luongo TS, Yamamoto T, Martí-Pàmies Í, Mia S, Latimer M, Diwan A, Zhao J, Hauck AK, Krusen B, Nguyen HCB, Blobel GA, Kelly DP, Pei L, Baur JA, Young ME, Lazar MA. Dierickx P, et al. Among authors: vermunt mw. Nat Cardiovasc Res. 2022 Jan;1(1):45-58. doi: 10.1038/s44161-021-00001-9. Epub 2021 Dec 23. Nat Cardiovasc Res. 2022. PMID: 35036997 Free PMC article.
Dissection of TAF1 neuronal splicing and implications for neurodegeneration in X-linked dystonia-parkinsonism.
Capponi S, Stöffler N, Penney EB, Grütz K, Nizamuddin S, Vermunt MW, Castelijns B, Fernandez-Cerado C, Legarda GP, Velasco-Andrada MS, Muñoz EL, Ang MA, Diesta CCE, Creyghton MP, Klein C, Bragg DC, De Rijk P, Timmers HTM. Capponi S, et al. Among authors: vermunt mw. Brain Commun. 2021 Oct 27;3(4):fcab253. doi: 10.1093/braincomms/fcab253. eCollection 2021. Brain Commun. 2021. PMID: 34746789 Free PMC article.
Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML.
Riedel SS, Lu C, Xie HM, Nestler K, Vermunt MW, Lenard A, Bennett L, Speck NA, Hanamura I, Lessard JA, Blobel GA, Garcia BA, Bernt KM. Riedel SS, et al. Among authors: vermunt mw. Mol Cell. 2021 Jun 3;81(11):2332-2348.e9. doi: 10.1016/j.molcel.2021.04.014. Epub 2021 May 10. Mol Cell. 2021. PMID: 33974912 Free PMC article.
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system.
Luan J, Xiang G, Gómez-García PA, Tome JM, Zhang Z, Vermunt MW, Zhang H, Huang A, Keller CA, Giardine BM, Zhang Y, Lan Y, Lis JT, Lakadamyali M, Hardison RC, Blobel GA. Luan J, et al. Among authors: vermunt mw. Cell Rep. 2021 Feb 23;34(8):108783. doi: 10.1016/j.celrep.2021.108783. Cell Rep. 2021. PMID: 33626344 Free PMC article.
25 results