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A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.
Fok ET, Moorlag SJCFM, Negishi Y, Groh LA, Dos Santos JC, Gräwe C, Monge VV, Craenmehr DDD, van Roosmalen M, da Cunha Jolvino DP, Migliorini LB, Neto AS, Severino P, Vermeulen M, Joosten LAB, Netea MG, Fanucchi S, Mhlanga MM. Fok ET, et al. Among authors: vermeulen m. Nat Genet. 2024 Jan;56(1):85-99. doi: 10.1038/s41588-023-01598-2. Epub 2023 Dec 13. Nat Genet. 2024. PMID: 38092881
Purification and enrichment of specific chromatin loci.
Gauchier M, van Mierlo G, Vermeulen M, Déjardin J. Gauchier M, et al. Among authors: vermeulen m. Nat Methods. 2020 Apr;17(4):380-389. doi: 10.1038/s41592-020-0765-4. Epub 2020 Mar 9. Nat Methods. 2020. PMID: 32152500 Review.
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma.
Choi J, Zhang T, Vu A, Ablain J, Makowski MM, Colli LM, Xu M, Hennessey RC, Yin J, Rothschild H, Gräwe C, Kovacs MA, Funderburk KM, Brossard M, Taylor J, Pasaniuc B, Chari R, Chanock SJ, Hoggart CJ, Demenais F, Barrett JH, Law MH, Iles MM, Yu K, Vermeulen M, Zon LI, Brown KM. Choi J, et al. Among authors: vermeulen m. Nat Commun. 2020 Jun 1;11(1):2718. doi: 10.1038/s41467-020-16590-1. Nat Commun. 2020. PMID: 32483191 Free PMC article.
Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons.
Rother N, Yanginlar C, Lindeboom RGH, Bekkering S, van Leent MMT, Buijsers B, Jonkman I, de Graaf M, Baltissen M, Lamers LA, Riksen NP, Fayad ZA, Mulder WJM, Hilbrands LB, Joosten LAB, Netea MG, Vermeulen M, van der Vlag J, Duivenvoorden R. Rother N, et al. Among authors: vermeulen m. Cell Rep Med. 2020 Nov 10;1(9):100146. doi: 10.1016/j.xcrm.2020.100146. eCollection 2020 Dec 22. Cell Rep Med. 2020. PMID: 33377122 Free PMC article.
BANP opens chromatin and activates CpG-island-regulated genes.
Grand RS, Burger L, Gräwe C, Michael AK, Isbel L, Hess D, Hoerner L, Iesmantavicius V, Durdu S, Pregnolato M, Krebs AR, Smallwood SA, Thomä N, Vermeulen M, Schübeler D. Grand RS, et al. Among authors: vermeulen m. Nature. 2021 Aug;596(7870):133-137. doi: 10.1038/s41586-021-03689-8. Epub 2021 Jul 7. Nature. 2021. PMID: 34234345
PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation.
Madsen MS, Broekema MF, Madsen MR, Koppen A, Borgman A, Gräwe C, Thomsen EGK, Westland D, Kranendonk MEG, Koerkamp MG, Hamers N, Bonvin AMJJ, Pittol JMR, Natarajan KN, Kersten S, Holstege FCP, Monajemi H, van Mil SWC, Vermeulen M, Kragelund BB, Cassiman D, Mandrup S, Kalkhoven E. Madsen MS, et al. Among authors: vermeulen m. Nat Commun. 2022 Nov 19;13(1):7090. doi: 10.1038/s41467-022-34766-9. Nat Commun. 2022. PMID: 36402763 Free PMC article.
1,033 results