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Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.
Yu X, Abeywickrema P, Bonneux B, Behera I, Anson B, Jacoby E, Fung A, Adhikary S, Bhaumik A, Carbajo RJ, De Bruyn S, Miller R, Patrick A, Pham Q, Piassek M, Verheyen N, Shareef A, Sutto-Ortiz P, Ysebaert N, Van Vlijmen H, Jonckers THM, Herschke F, McLellan JS, Decroly E, Fearns R, Grosse S, Roymans D, Sharma S, Rigaux P, Jin Z. Yu X, et al. Among authors: verheyen n. Commun Biol. 2023 Oct 21;6(1):1074. doi: 10.1038/s42003-023-05451-4. Commun Biol. 2023. PMID: 37865687 Free PMC article.
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.
Roymans D, Alnajjar SS, Battles MB, Sitthicharoenchai P, Furmanova-Hollenstein P, Rigaux P, Berg JVD, Kwanten L, Ginderen MV, Verheyen N, Vranckx L, Jaensch S, Arnoult E, Voorzaat R, Gallup JM, Larios-Mora A, Crabbe M, Huntjens D, Raboisson P, Langedijk JP, Ackermann MR, McLellan JS, Vendeville S, Koul A. Roymans D, et al. Among authors: verheyen n. Nat Commun. 2017 Aug 1;8(1):167. doi: 10.1038/s41467-017-00170-x. Nat Commun. 2017. PMID: 28761099 Free PMC article.
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein.
Roymans D, De Bondt HL, Arnoult E, Geluykens P, Gevers T, Van Ginderen M, Verheyen N, Kim H, Willebrords R, Bonfanti JF, Bruinzeel W, Cummings MD, van Vlijmen H, Andries K. Roymans D, et al. Among authors: verheyen n. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):308-13. doi: 10.1073/pnas.0910108106. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966279 Free PMC article.
Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library.
Hernandez-Morales I, Geluykens P, Clynhens M, Strijbos R, Goethals O, Megens S, Verheyen N, Last S, McGowan D, Coesemans E, De Boeck B, Stoops B, Devogelaere B, Pauwels F, Vandyck K, Berke JM, Raboisson P, Simmen K, Lory P, Van Loock M. Hernandez-Morales I, et al. Among authors: verheyen n. Antiviral Res. 2017 Nov;147:149-158. doi: 10.1016/j.antiviral.2017.10.011. Epub 2017 Oct 14. Antiviral Res. 2017. PMID: 29037976
Prevalence and prognostic impact of bone disease in chronic heart failure with reduced ejection fraction.
Verheyen N, Schmid J, Kolesnik E, Schwegel N, Späth J, Kattnig L, Riepl H, Zach D, Santner V, Höller V, Pilz S, Tomaschitz A, Fuchsjäger M, Fahrleitner-Pammer A, Dimai HP, Obermayer-Pietsch B, Fruhwald F, Scherr D, Zirlik A, von Lewinski D, Ablasser K. Verheyen N, et al. ESC Heart Fail. 2024 Mar 7. doi: 10.1002/ehf2.14741. Online ahead of print. ESC Heart Fail. 2024. PMID: 38450879 Free article.
Low-grade systemic inflammation and left ventricular dysfunction in hypertensive compared to non-hypertensive hypertrophic cardiomyopathy.
Zach DK, Schwegel N, Santner V, Winkelbauer L, Hoeller V, Kolesnik E, Gollmer J, Seggewiss H, Batzner A, Perl S, Wallner M, Reiter U, Rainer PP, Zirlik A, Ablasser K, Verheyen N. Zach DK, et al. Among authors: verheyen n. Int J Cardiol. 2024 Mar 15;399:131661. doi: 10.1016/j.ijcard.2023.131661. Epub 2023 Dec 27. Int J Cardiol. 2024. PMID: 38158132 Free article.
Outcomes of ECLS-SHOCK Eligibility Criteria Applied to a Real-World Cohort.
von Lewinski D, Herold L, Bachl E, Bugger H, Glantschnig T, Kolesnik E, Verheyen N, Benedikt M, Wallner M, von Lewinski F, Schmidt A, Harb S, Ablasser K, Sacherer M, Scherr D, Manninger-Wünscher M, Pätzold S, Gollmer J, Zirlik A, Toth GG. von Lewinski D, et al. Among authors: verheyen n. J Clin Med. 2023 Nov 8;12(22):6988. doi: 10.3390/jcm12226988. J Clin Med. 2023. PMID: 38002602 Free PMC article.
A truncated HIV Tat demonstrates potent and specific latency reversal activity.
Van Gulck E, Pardons M, Nijs E, Verheyen N, Dockx K, Van Den Eynde C, Battivelli E, Vega J, Florence E, Autran B, Archin NM, Margolis DM, Katlama C, Hamimi C, Van Den Wyngaert I, Eyassu F, Vandekerckhove L, Boden D. Van Gulck E, et al. Among authors: verheyen n. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0041723. doi: 10.1128/aac.00417-23. Epub 2023 Oct 24. Antimicrob Agents Chemother. 2023. PMID: 37874295 Free PMC article.
115 results