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Duodenal macrophages control dietary iron absorption via local degradation of transferrin.
Sukhbaatar N, Schöller M, Fritsch SD, Linke M, Horer S, Träger M, Mazić M, Forisch S, Gonzales K, Kahler JP, Binder C, Lassnig C, Strobl B, Müller M, Scheiber-Mojdehkar B, Gundacker C, Dabsch S, Kain R, Hengstschläger M, Verhelst SHL, Weiss G, Theurl I, Weichhart T. Sukhbaatar N, et al. Among authors: verhelst shl. Blood. 2023 Jun 8;141(23):2878-2890. doi: 10.1182/blood.2022016632. Blood. 2023. PMID: 37018657 Free PMC article.
Inhibitors of rhomboid proteases.
Wolf EV, Verhelst SH. Wolf EV, et al. Biochimie. 2016 Mar;122:38-47. doi: 10.1016/j.biochi.2015.07.007. Epub 2015 Jul 10. Biochimie. 2016. PMID: 26166068 Free article. Review.
Chemical Tools for the Study of Intramembrane Proteases.
Nguyen MT, Van Kersavond T, Verhelst SH. Nguyen MT, et al. ACS Chem Biol. 2015 Nov 20;10(11):2423-34. doi: 10.1021/acschembio.5b00693. Epub 2015 Nov 5. ACS Chem Biol. 2015. PMID: 26473325 Review.
General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Tichá A, Stanchev S, Vinothkumar KR, Mikles DC, Pachl P, Began J, Škerle J, Švehlová K, Nguyen MTN, Verhelst SHL, Johnson DC, Bachovchin DA, Lepšík M, Majer P, Strisovsky K. Tichá A, et al. Among authors: verhelst shl. Cell Chem Biol. 2017 Dec 21;24(12):1523-1536.e4. doi: 10.1016/j.chembiol.2017.09.007. Epub 2017 Oct 26. Cell Chem Biol. 2017. PMID: 29107700 Free PMC article.
Discovery and Biological Evaluation of Potent and Selective N-Methylene Saccharin-Derived Inhibitors for Rhomboid Intramembrane Proteases.
Goel P, Jumpertz T, Mikles DC, Tichá A, Nguyen MTN, Verhelst S, Hubalek M, Johnson DC, Bachovchin DA, Ogorek I, Pietrzik CU, Strisovsky K, Schmidt B, Weggen S. Goel P, et al. Biochemistry. 2017 Dec 26;56(51):6713-6725. doi: 10.1021/acs.biochem.7b01066. Epub 2017 Dec 12. Biochemistry. 2017. PMID: 29185711 Free PMC article.
97 results