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Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.
Bhat VK, Bernhart E, Plastira I, Fan K, Ghaffari-Tabrizi-Wizsy N, Wadsack C, Rechberger G, Eichmann T, Asslaber M, Spassova I, Verhaegen ME, Malle E, Becker JC, Sattler W. Bhat VK, et al. Among authors: verhaegen me. J Invest Dermatol. 2019 Apr;139(4):807-817. doi: 10.1016/j.jid.2018.10.024. Epub 2018 Nov 3. J Invest Dermatol. 2019. PMID: 30399362 Free article.
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis.
Harms PW, Patel RM, Verhaegen ME, Giordano TJ, Nash KT, Johnson CN, Daignault S, Thomas DG, Gudjonsson JE, Elder JT, Dlugosz AA, Johnson TM, Fullen DR, Bichakjian CK. Harms PW, et al. Among authors: verhaegen me. J Invest Dermatol. 2013 Apr;133(4):936-45. doi: 10.1038/jid.2012.445. Epub 2012 Dec 6. J Invest Dermatol. 2013. PMID: 23223137 Free PMC article.
Merkel cell carcinoma dependence on bcl-2 family members for survival.
Verhaegen ME, Mangelberger D, Weick JW, Vozheiko TD, Harms PW, Nash KT, Quintana E, Baciu P, Johnson TM, Bichakjian CK, Dlugosz AA. Verhaegen ME, et al. J Invest Dermatol. 2014 Aug;134(8):2241-2250. doi: 10.1038/jid.2014.138. Epub 2014 Mar 10. J Invest Dermatol. 2014. PMID: 24614157 Free PMC article.
Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.
Verhaegen ME, Mangelberger D, Harms PW, Vozheiko TD, Weick JW, Wilbert DM, Saunders TL, Ermilov AN, Bichakjian CK, Johnson TM, Imperiale MJ, Dlugosz AA. Verhaegen ME, et al. J Invest Dermatol. 2015 May;135(5):1415-1424. doi: 10.1038/jid.2014.446. Epub 2014 Oct 14. J Invest Dermatol. 2015. PMID: 25313532 Free PMC article.
The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma.
Harms PW, Vats P, Verhaegen ME, Robinson DR, Wu YM, Dhanasekaran SM, Palanisamy N, Siddiqui J, Cao X, Su F, Wang R, Xiao H, Kunju LP, Mehra R, Tomlins SA, Fullen DR, Bichakjian CK, Johnson TM, Dlugosz AA, Chinnaiyan AM. Harms PW, et al. Among authors: verhaegen me. Cancer Res. 2015 Sep 15;75(18):3720-3727. doi: 10.1158/0008-5472.CAN-15-0702. Epub 2015 Aug 3. Cancer Res. 2015. PMID: 26238782 Free PMC article.
Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation.
Harms PW, Collie AM, Hovelson DH, Cani AK, Verhaegen ME, Patel RM, Fullen DR, Omata K, Dlugosz AA, Tomlins SA, Billings SD. Harms PW, et al. Among authors: verhaegen me. Mod Pathol. 2016 Mar;29(3):240-8. doi: 10.1038/modpathol.2015.154. Epub 2016 Jan 8. Mod Pathol. 2016. PMID: 26743471 Free PMC article.
Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma.
Fan K, Ritter C, Nghiem P, Blom A, Verhaegen ME, Dlugosz A, Ødum N, Woetmann A, Tothill RW, Hicks RJ, Sand M, Schrama D, Schadendorf D, Ugurel S, Becker JC. Fan K, et al. Among authors: verhaegen me. Clin Cancer Res. 2018 Dec 1;24(23):5873-5882. doi: 10.1158/1078-0432.CCR-18-1184. Epub 2018 Jul 30. Clin Cancer Res. 2018. PMID: 30061360 Free PMC article.
Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.
Choi JE, Verhaegen ME, Yazdani S, Malik R, Harms PW, Mangelberger D, Tien J, Cao X, Wang Y, Cieślik M, Gurkan J, Yazdani M, Jing X, Juckette K, Su F, Wang R, Zhou B, Apel IJ, Wang S, Dlugosz AA, Chinnaiyan AM. Choi JE, et al. Among authors: verhaegen me. Neoplasia. 2019 Mar;21(3):322-330. doi: 10.1016/j.neo.2019.01.003. Epub 2019 Feb 21. Neoplasia. 2019. PMID: 30797188 Free PMC article.
42 results