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Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth.
Verginelli F, Perin A, Dali R, Fung KH, Lo R, Longatti P, Guiot MC, Del Maestro RF, Rossi S, di Porzio U, Stechishin O, Weiss S, Stifani S. Verginelli F, et al. Nat Commun. 2013;4:2956. doi: 10.1038/ncomms3956. Nat Commun. 2013. PMID: 24356439 Free PMC article.
MET inhibition overcomes radiation resistance of glioblastoma stem-like cells.
De Bacco F, D'Ambrosio A, Casanova E, Orzan F, Neggia R, Albano R, Verginelli F, Cominelli M, Poliani PL, Luraghi P, Reato G, Pellegatta S, Finocchiaro G, Perera T, Garibaldi E, Gabriele P, Comoglio PM, Boccaccio C. De Bacco F, et al. Among authors: verginelli f. EMBO Mol Med. 2016 May 2;8(5):550-68. doi: 10.15252/emmm.201505890. Print 2016 May. EMBO Mol Med. 2016. PMID: 27138567 Free PMC article.
Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary.
Brundu S, Napolitano V, Franzolin G, Lo Cascio E, Mastrantonio R, Sardo G, Cascardi E, Verginelli F, Sarnataro S, Gambardella G, Pisacane A, Arcovito A, Boccaccio C, Comoglio PM, Giraudo E, Tamagnone L. Brundu S, et al. Among authors: verginelli f. EMBO Mol Med. 2023 Mar 8;15(3):e16104. doi: 10.15252/emmm.202216104. Epub 2023 Feb 1. EMBO Mol Med. 2023. PMID: 36722641 Free PMC article.
An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.
Kulasekaran G, Chaineau M, Piscopo VEC, Verginelli F, Fotouhi M, Girard M, Tang Y, Dali R, Lo R, Stifani S, McPherson PS. Kulasekaran G, et al. Among authors: verginelli f. J Cell Biol. 2021 Feb 1;220(2):e202004229. doi: 10.1083/jcb.202004229. J Cell Biol. 2021. PMID: 33443570 Free PMC article.
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).
Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini PP, Dall'Agnese A, Walters ZS, Verginelli F, De Sio L, Boldrini R, Inserra A, Bisogno G, Rosolen A, Alaggio R, Ferrari A, Collini P, Locatelli M, Stifani S, Screpanti I, Rutella S, Yu Q, Marquez VE, Shipley J, Valente S, Mai A, Miele L, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: verginelli f. Oncogene. 2014 Aug 7;33(32):4173-84. doi: 10.1038/onc.2013.471. Epub 2013 Nov 11. Oncogene. 2014. PMID: 24213577
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini PP, Dall'agnese A, Verginelli F, Milano GM, Boldrini R, Inserra A, Stifani S, Screpanti I, Marquez VE, Valente S, Mai A, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: verginelli f. BMC Cancer. 2014 Feb 27;14:139. doi: 10.1186/1471-2407-14-139. BMC Cancer. 2014. PMID: 24575771 Free PMC article.
Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.
De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, Alaggio R, Inserra A, Locatelli M, Stifani S, Screpanti I, Miele L, Locatelli F, Rota R. De Salvo M, et al. Among authors: verginelli f. PLoS One. 2014 May 5;9(5):e96238. doi: 10.1371/journal.pone.0096238. eCollection 2014. PLoS One. 2014. PMID: 24797362 Free PMC article.
71 results