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From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions.
Tiane A, Schepers M, Reijnders RA, van Veggel L, Chenine S, Rombaut B, Dempster E, Verfaillie C, Wasner K, Grünewald A, Prickaerts J, Pishva E, Hellings N, van den Hove D, Vanmierlo T. Tiane A, et al. Among authors: verfaillie c. Acta Neuropathol. 2023 Aug;146(2):283-299. doi: 10.1007/s00401-023-02596-8. Epub 2023 Jun 7. Acta Neuropathol. 2023. PMID: 37286732 Free PMC article.
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Schepers M, Paes D, Tiane A, Rombaut B, Piccart E, van Veggel L, Gervois P, Wolfs E, Lambrichts I, Brullo C, Bruno O, Fedele E, Ricciarelli R, Ffrench-Constant C, Bechler ME, van Schaik P, Baron W, Lefevere E, Wasner K, Grünewald A, Verfaillie C, Baeten P, Broux B, Wieringa P, Hellings N, Prickaerts J, Vanmierlo T. Schepers M, et al. Among authors: verfaillie c. Brain Behav Immun. 2023 Mar;109:1-22. doi: 10.1016/j.bbi.2022.12.020. Epub 2022 Dec 28. Brain Behav Immun. 2023. PMID: 36584795 Free article.
Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.
Chandrasekaran V, Wellens S, Bourguignon A, Djidrovski I, Fransen L, Ghosh S, Mazidi Z, Murphy C, Nunes C, Singh P, Zana M, Armstrong L, Dinnyés A, Grillari J, Grillari-Voglauer R, Leonard MO, Verfaillie C, Wilmes A, Zurich MG, Exner T, Jennings P, Culot M. Chandrasekaran V, et al. Among authors: verfaillie c. Toxicol In Vitro. 2024 Apr 12;98:105826. doi: 10.1016/j.tiv.2024.105826. Online ahead of print. Toxicol In Vitro. 2024. PMID: 38615723 Free article.
Elevated α-synuclein levels inhibit mitophagic flux.
Kinnart I, Manders L, Heyninck T, Imberechts D, Praschberger R, Schoovaerts N, Verfaillie C, Verstreken P, Vandenberghe W. Kinnart I, et al. Among authors: verfaillie c. NPJ Parkinsons Dis. 2024 Apr 9;10(1):80. doi: 10.1038/s41531-024-00696-0. NPJ Parkinsons Dis. 2024. PMID: 38594264 Free PMC article.
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology.
Mancuso R, Fattorelli N, Martinez-Muriana A, Davis E, Wolfs L, Van Den Daele J, Geric I, Premereur J, Polanco P, Bijnens B, Preman P, Serneels L, Poovathingal S, Balusu S, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: verfaillie c. Nat Neurosci. 2024 May;27(5):886-900. doi: 10.1038/s41593-024-01600-y. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539015 Free PMC article.
Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic: role of the Belgian National Reference Centre.
Janssen R, Cuypers L, Laenen L, Keyaerts E, Beuselinck K, Janssenswillen S, Slechten B, Bode J, Wollants E, Van Laethem K, Rector A, Bloemen M, Sijmons A, de Schaetzen N, Capron A, Van Baelen K, Pascal T, Vermeiren C, Bureau F, Vandesompele J, De Smet P, Uten W, Malonne H, Kerkhofs P, De Cock J, Matheeussen V, Verhasselt B, Gillet L, Detry G, Bearzatto B, Degosserie J, Henin C, Pairoux G; COVID-19 Genomics Belgium Consortium; Maes P, Van Ranst M, Lagrou K, Dequeker E, André E. Janssen R, et al. Virol J. 2024 Feb 10;21(1):40. doi: 10.1186/s12985-024-02308-y. Virol J. 2024. PMID: 38341597 Free PMC article. Review.
468 results