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Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential.
Becker AMD, Decker AH, Flórez-Grau G, Bakdash G, Röring RJ, Stelloo S, Vermeulen M, Piet B, Aarntzen EHJG, Verdoes M, de Vries IJM. Becker AMD, et al. Among authors: verdoes m. Cell Rep Med. 2024 Feb 20;5(2):101386. doi: 10.1016/j.xcrm.2023.101386. Epub 2024 Jan 18. Cell Rep Med. 2024. PMID: 38242119 Free PMC article.
CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells.
Gall CLM, Fennemann FL, Van Der Schoot JMS, Scheeren FA, Verdoes M. Gall CLM, et al. Among authors: verdoes m. Bio Protoc. 2023 Feb 20;13(4):e4613. doi: 10.21769/BioProtoc.4613. eCollection 2023 Feb 20. Bio Protoc. 2023. PMID: 36845533 Free PMC article.
Effect of Antigen Valency on Autoreactive B-Cell Targeting.
van Weijsten MJ, Venrooij KR, Lelieveldt LPWM, Kissel T, van Buijtenen E, van Dalen FJ, Verdoes M, Toes REM, Bonger KM. van Weijsten MJ, et al. Among authors: verdoes m. Mol Pharm. 2024 Feb 5;21(2):481-490. doi: 10.1021/acs.molpharmaceut.3c00527. Epub 2023 Oct 20. Mol Pharm. 2024. PMID: 37862070 Free PMC article.
Direct In Vivo Activation of T Cells with Nanosized Immunofilaments Inhibits Tumor Growth and Metastasis.
Weiss L, Weiden J, Dölen Y, Grad EM, van Dinther EAW, Schluck M, Eggermont LJ, van Mierlo G, Gileadi U, Bartoló-Ibars A, Raavé R, Gorris MAJ, Maassen L, Verrijp K, Valente M, Deplancke B, Verdoes M, Benitez-Ribas D, Heskamp S, van Spriel AB, Figdor CG, Hammink R. Weiss L, et al. Among authors: verdoes m. ACS Nano. 2023 Jul 11;17(13):12101-12117. doi: 10.1021/acsnano.2c11884. Epub 2023 Jun 20. ACS Nano. 2023. PMID: 37338806 Free PMC article.
PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance.
van Gulijk M, van Krimpen A, Schetters S, Eterman M, van Elsas M, Mankor J, Klaase L, de Bruijn M, van Nimwegen M, van Tienhoven T, van Ijcken W, Boon L, van der Schoot J, Verdoes M, Scheeren F, van der Burg SH, Lambrecht BN, Stadhouders R, Dammeijer F, Aerts J, van Hall T. van Gulijk M, et al. Among authors: verdoes m. Sci Immunol. 2023 May 19;8(83):eabn6173. doi: 10.1126/sciimmunol.abn6173. Epub 2023 May 19. Sci Immunol. 2023. PMID: 37205768
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