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NAD+ metabolism and its roles in cellular processes during ageing.
Covarrubias AJ, Perrone R, Grozio A, Verdin E. Covarrubias AJ, et al. Among authors: verdin e. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141. doi: 10.1038/s41580-020-00313-x. Epub 2020 Dec 22. Nat Rev Mol Cell Biol. 2021. PMID: 33353981 Free PMC article. Review.
Regulation of urea cycle by reversible high-stoichiometry lysine succinylation.
Zhang R, Fang J, Xie X, Carrico C, Meyer JG, Wei L, Bons J, Rose J, Riley R, Kwok R, Ashok Kumaar PV, Zhang Y, He W, Nishida Y, Liu X, Locasale JW, Schilling B, Verdin E. Zhang R, et al. Among authors: verdin e. Nat Metab. 2024 Mar;6(3):550-566. doi: 10.1038/s42255-024-01005-y. Epub 2024 Mar 6. Nat Metab. 2024. PMID: 38448615
Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease.
Amano H, Chaudhury A, Rodriguez-Aguayo C, Lu L, Akhanov V, Catic A, Popov YV, Verdin E, Johnson H, Stossi F, Sinclair DA, Nakamaru-Ogiso E, Lopez-Berestein G, Chang JT, Neilson JR, Meeker A, Finegold M, Baur JA, Sahin E. Amano H, et al. Among authors: verdin e. Cell Metab. 2019 Jun 4;29(6):1274-1290.e9. doi: 10.1016/j.cmet.2019.03.001. Epub 2019 Mar 28. Cell Metab. 2019. PMID: 30930169 Free PMC article.
NAD+-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism.
Porter LC, Franczyk MP, Pietka T, Yamaguchi S, Lin JB, Sasaki Y, Verdin E, Apte RS, Yoshino J. Porter LC, et al. Among authors: verdin e. Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E520-E530. doi: 10.1152/ajpendo.00057.2018. Epub 2018 Apr 10. Am J Physiol Endocrinol Metab. 2018. PMID: 29634313 Free PMC article.
Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Dikalova AE, Pandey A, Xiao L, Arslanbaeva L, Sidorova T, Lopez MG, Billings FT 4th, Verdin E, Auwerx J, Harrison DG, Dikalov SI. Dikalova AE, et al. Among authors: verdin e. Circ Res. 2020 Feb 14;126(4):439-452. doi: 10.1161/CIRCRESAHA.119.315767. Epub 2019 Dec 19. Circ Res. 2020. PMID: 31852393 Free PMC article.
Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure.
Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD. Yurista SR, et al. Among authors: verdin e. Circ Heart Fail. 2021 Jan;14(1):e007684. doi: 10.1161/CIRCHEARTFAILURE.120.007684. Epub 2020 Dec 28. Circ Heart Fail. 2021. PMID: 33356362 Free PMC article.
Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.
Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J. Wiley CD, et al. Among authors: verdin e. Cell Metab. 2016 Feb 9;23(2):303-14. doi: 10.1016/j.cmet.2015.11.011. Epub 2015 Dec 10. Cell Metab. 2016. PMID: 26686024 Free PMC article.
337 results