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Phase 1/2 Trial Results of a Large Surface Area Microparticle Docetaxel for the Treatment of High-Risk Nonmuscle-Invasive Bladder Cancer.
J Urol. 2022 Oct;208(4):821-829. doi: 10.1097/JU.0000000000002778. Epub 2022 May 16.
J Urol. 2022.
PMID: 35574612
Clinical Trial.
Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac®) in a Rodent Model.
Verco J, Johnston W, Baltezor M, Kuehl PJ, Gigliotti A, Belinsky SA, Lopez A, Wolff R, Hylle L, diZerega G.
Verco J, et al.
J Aerosol Med Pulm Drug Deliv. 2019 Apr;32(2):99-109. doi: 10.1089/jamp.2018.1467. Epub 2018 Oct 25.
J Aerosol Med Pulm Drug Deliv. 2019.
PMID: 30359162
Free PMC article.
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Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer.
Verco J, Johnston W, Frost M, Baltezor M, Kuehl PJ, Lopez A, Gigliotti A, Belinsky SA, Wolff R, diZerega G.
Verco J, et al.
J Aerosol Med Pulm Drug Deliv. 2019 Oct;32(5):266-277. doi: 10.1089/jamp.2018.1517. Epub 2019 Jul 26.
J Aerosol Med Pulm Drug Deliv. 2019.
PMID: 31347939
Free PMC article.
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Local administration of submicron particle paclitaxel to solid carcinomas induces direct cytotoxicity and immune-mediated tumoricidal effects without local or systemic toxicity: preclinical and clinical studies.
Verco S, Maulhardt H, Baltezor M, Williams E, Iacobucci M, Wendt A, Verco J, Marin A, Campbell S, Dorman P, diZerega G.
Verco S, et al. Among authors: verco j.
Drug Deliv Transl Res. 2021 Oct;11(5):1806-1817. doi: 10.1007/s13346-020-00868-4. Epub 2020 Nov 6.
Drug Deliv Transl Res. 2021.
PMID: 33159289
Free PMC article.
Review.
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Early phase trial of intracystic injection of large surface area microparticle paclitaxel for treatment of mucinous pancreatic cysts.
Othman M, Patel K, Krishna SG, Mendoza-Ladd A, Verco S, Abidi W, Verco J, Wendt A, diZerega G.
Othman M, et al. Among authors: verco j.
Endosc Int Open. 2022 Dec 15;10(12):E1517-E1525. doi: 10.1055/a-1949-7730. eCollection 2022 Dec.
Endosc Int Open. 2022.
PMID: 36531683
Free PMC article.
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Response of Locally Advanced Pancreatic Cancer to Intratumoral Injection of Large Surface Area Microparticle Paclitaxel: Initial Report of Safety and Clinical Outcome.
Sharma NR, Lo SK, Hendifar A, Othman MO, Patel K, Mendoza-Ladd A, Verco S, Maulhardt HA, Verco J, Wendt A, Marin A, Schmidt CM, diZerega G.
Sharma NR, et al. Among authors: verco j.
Pancreas. 2023 Mar 1;52(3):e179-e187. doi: 10.1097/MPA.0000000000002236.
Pancreas. 2023.
PMID: 37782888
Clinical Trial.
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