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Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
de Rooij JD, Branstetter C, Ma J, Li Y, Walsh MP, Cheng J, Obulkasim A, Dang J, Easton J, Verboon LJ, Mulder HL, Zimmermann M, Koss C, Gupta P, Edmonson M, Rusch M, Lim JY, Reinhardt K, Pigazzi M, Song G, Yeoh AE, Shih LY, Liang DC, Halene S, Krause DS, Zhang J, Downing JR, Locatelli F, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M, Gruber TA. de Rooij JD, et al. Among authors: verboon lj. Nat Genet. 2017 Mar;49(3):451-456. doi: 10.1038/ng.3772. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112737 Free PMC article.
BCOR and BCORL1 mutations in pediatric acute myeloid leukemia.
de Rooij JD, van den Heuvel-Eibrink MM, Hermkens MC, Verboon LJ, Arentsen-Peters ST, Fornerod M, Baruchel A, Stary J, Reinhardt D, de Haas V, Pieters R, Zwaan CM. de Rooij JD, et al. Among authors: verboon lj. Haematologica. 2015 May;100(5):e194-5. doi: 10.3324/haematol.2014.117796. Epub 2015 Jan 16. Haematologica. 2015. PMID: 25596268 Free PMC article. No abstract available.
PHF6 mutations in paediatric acute myeloid leukaemia.
de Rooij JD, van den Heuvel-Eibrink MM, van de Rijdt NK, Verboon LJ, de Haas V, Trka J, Baruchel A, Reinhardt D, Pieters R, Fornerod M, Zwaan CM. de Rooij JD, et al. Among authors: verboon lj. Br J Haematol. 2016 Dec;175(5):967-971. doi: 10.1111/bjh.13891. Epub 2015 Dec 21. Br J Haematol. 2016. PMID: 27885656 Free article. No abstract available.
Mapping epigenetic regulator gene mutations in cytogenetically normal pediatric acute myeloid leukemia.
Valerio DG, Katsman-Kuipers JE, Jansen JH, Verboon LJ, de Haas V, Stary J, Baruchel A, Zimmermann M, Pieters R, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM. Valerio DG, et al. Among authors: verboon lj. Haematologica. 2014 Aug;99(8):e130-2. doi: 10.3324/haematol.2013.094565. Epub 2014 May 9. Haematologica. 2014. PMID: 24816242 Free PMC article. No abstract available.
miR-9 is a tumor suppressor in pediatric AML with t(8;21).
Emmrich S, Katsman-Kuipers JE, Henke K, Khatib ME, Jammal R, Engeland F, Dasci F, Zwaan CM, den Boer ML, Verboon L, Stary J, Baruchel A, de Haas V, Danen-van Oorschot AA, Fornerod M, Pieters R, Reinhardt D, Klusmann JH, van den Heuvel-Eibrink MM. Emmrich S, et al. Leukemia. 2014 May;28(5):1022-32. doi: 10.1038/leu.2013.357. Epub 2013 Nov 25. Leukemia. 2014. PMID: 24270738
Low frequency of DNMT3A mutations in pediatric AML, and the identification of the OCI-AML3 cell line as an in vitro model.
Hollink IH, Feng Q, Danen-van Oorschot AA, Arentsen-Peters ST, Verboon LJ, Zhang P, de Haas V, Reinhardt D, Creutzig U, Trka J, Pieters R, van den Heuvel-Eibrink MM, Wang J, Zwaan CM. Hollink IH, et al. Among authors: verboon lj. Leukemia. 2012 Feb;26(2):371-3. doi: 10.1038/leu.2011.210. Epub 2011 Aug 12. Leukemia. 2012. PMID: 21836609 No abstract available.