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CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.
Dunbar AJ, Kim D, Lu M, Farina M, Bowman RL, Yang JL, Park Y, Karzai A, Xiao W, Zaroogian Z, O'Connor K, Mowla S, Gobbo F, Verachi P, Martelli F, Sarli G, Xia L, Elmansy N, Kleppe M, Chen Z, Xiao Y, McGovern E, Snyder J, Krishnan A, Hill C, Cordner K, Zouak A, Salama ME, Yohai J, Tucker E, Chen J, Zhou J, McConnell T, Migliaccio AR, Koche R, Rampal R, Fan R, Levine RL, Hoffman R. Dunbar AJ, et al. Among authors: verachi p. Blood. 2023 May 18;141(20):2508-2519. doi: 10.1182/blood.2022015418. Blood. 2023. PMID: 36800567 Free PMC article.
Novel targets to cure primary myelofibrosis from studies on Gata1low mice.
Zingariello M, Martelli F, Verachi P, Bardelli C, Gobbo F, Mazzarini M, Migliaccio AR. Zingariello M, et al. Among authors: verachi p. IUBMB Life. 2020 Jan;72(1):131-141. doi: 10.1002/iub.2198. Epub 2019 Nov 21. IUBMB Life. 2020. PMID: 31749302 Free PMC article. Review.
TGF-β1 protein trap AVID200 beneficially affects hematopoiesis and bone marrow fibrosis in myelofibrosis.
Varricchio L, Iancu-Rubin C, Upadhyaya B, Zingariello M, Martelli F, Verachi P, Clementelli C, Denis JF, Rahman AH, Tremblay G, Mascarenhas J, Mesa RA, O'Connor-McCourt M, Migliaccio AR, Hoffman R. Varricchio L, et al. Among authors: verachi p. JCI Insight. 2021 Sep 22;6(18):e145651. doi: 10.1172/jci.insight.145651. JCI Insight. 2021. PMID: 34383713 Free PMC article.
Role of β1 integrin in thrombocytopoiesis.
Mazzarini M, Verachi P, Martelli F, Migliaccio AR. Mazzarini M, et al. Among authors: verachi p. Fac Rev. 2021 Sep 1;10:68. doi: 10.12703/r/10-68. eCollection 2021. Fac Rev. 2021. PMID: 34557872 Free PMC article. Review.
Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in Gata1low Mice.
Zingariello M, Verachi P, Gobbo F, Martelli F, Falchi M, Mazzarini M, Valeri M, Sarli G, Marinaccio C, Melo-Cardenas J, Crispino JD, Migliaccio AR. Zingariello M, et al. Among authors: verachi p. Biomolecules. 2022 Jan 30;12(2):234. doi: 10.3390/biom12020234. Biomolecules. 2022. PMID: 35204735 Free PMC article.
Single cell analysis of the localization of the hematopoietic stem cells within the bone marrow architecture identifies niche-specific proliferation dynamics.
Mazzarini M, Arciprete F, Picconi O, Valeri M, Verachi P, Martelli F, Migliaccio AR, Falchi M, Zingariello M. Mazzarini M, et al. Among authors: verachi p. Front Med (Lausanne). 2023 Apr 28;10:1166758. doi: 10.3389/fmed.2023.1166758. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37188088 Free PMC article.
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