Venugopal H - Search Results

1

Positive allosteric mechanisms of adenosine A₁ receptor-mediated analgesia.

Draper-Joyce CJ, Bhola R, Wang J, Bhattarai A, Nguyen ATN, Cowie-Kent I, O'Sullivan K, Chia LY, Venugopal H, Valant C, Thal DM, Wootten D, Panel N, Carlsson J, Christie MJ, White PJ, Scammells P, May LT, Sexton PM, Danev R, Miao Y, Glukhova A, Imlach WL, Christopoulos A. Draper-Joyce CJ, et al. Among authors: venugopal h. Nature. 2021 Sep;597(7877):571-576. doi: 10.1038/s41586-021-03897-2. Epub 2021 Sep 8. Nature. 2021. PMID: 34497422 Free PMC article.

2

Structure of the adenosine-bound human adenosine A₁ receptor-G_i complex.

Draper-Joyce CJ, Khoshouei M, Thal DM, Liang YL, Nguyen ATN, Furness SGB, Venugopal H, Baltos JA, Plitzko JM, Danev R, Baumeister W, May LT, Wootten D, Sexton PM, Glukhova A, Christopoulos A. Draper-Joyce CJ, et al. Among authors: venugopal h. Nature. 2018 Jun;558(7711):559-563. doi: 10.1038/s41586-018-0236-6. Epub 2018 Jun 20. Nature. 2018. PMID: 29925945

3

Molecular basis for control of antibiotic production by a bacterial hormone.

Zhou S, Bhukya H, Malet N, Harrison PJ, Rea D, Belousoff MJ, Venugopal H, Sydor PK, Styles KM, Song L, Cryle MJ, Alkhalaf LM, Fülöp V, Challis GL, Corre C. Zhou S, et al. Among authors: venugopal h. Nature. 2021 Feb;590(7846):463-467. doi: 10.1038/s41586-021-03195-x. Epub 2021 Feb 3. Nature. 2021. PMID: 33536618

4

Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.

Horne CR, Venugopal H, Panjikar S, Wood DM, Henrickson A, Brookes E, North RA, Murphy JM, Friemann R, Griffin MDW, Ramm G, Demeler B, Dobson RCJ. Horne CR, et al. Among authors: venugopal h. Nat Commun. 2021 Mar 31;12(1):1988. doi: 10.1038/s41467-021-22253-6. Nat Commun. 2021. PMID: 33790291 Free PMC article.

5

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses.

Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D. Hardy JM, et al. Among authors: venugopal h. Nat Commun. 2021 Jun 1;12(1):3266. doi: 10.1038/s41467-021-22773-1. Nat Commun. 2021. PMID: 34075032 Free PMC article.

6

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.

Wheatley AK, Pymm P, Esterbauer R, Dietrich MH, Lee WS, Drew D, Kelly HG, Chan LJ, Mordant FL, Black KA, Adair A, Tan HX, Juno JA, Wragg KM, Amarasena T, Lopez E, Selva KJ, Haycroft ER, Cooney JP, Venugopal H, Tan LL, O Neill MT, Allison CC, Cromer D, Davenport MP, Bowen RA, Chung AW, Pellegrini M, Liddament MT, Glukhova A, Subbarao K, Kent SJ, Tham WH. Wheatley AK, et al. Among authors: venugopal h. Cell Rep. 2021 Oct 12;37(2):109822. doi: 10.1016/j.celrep.2021.109822. Epub 2021 Sep 25. Cell Rep. 2021. PMID: 34610292 Free PMC article.

7

Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.

Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A. Mobbs JI, et al. Among authors: venugopal h. Blood. 2023 Oct 5;142(14):1233-1242. doi: 10.1182/blood.2023020441. Blood. 2023. PMID: 37506345

8

Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.

Russell IC, Zhang X, Bumbak F, McNeill SM, Josephs TM, Leeming MG, Christopoulos G, Venugopal H, Flocco MM, Sexton PM, Wootten D, Belousoff MJ. Russell IC, et al. Among authors: venugopal h. Biochemistry. 2024 Mar 5;63(5):625-631. doi: 10.1021/acs.biochem.3c00647. Epub 2024 Feb 20. Biochemistry. 2024. PMID: 38376112

9

The first transmembrane region of complement component-9 acts as a brake on its self-assembly.

Spicer BA, Law RHP, Caradoc-Davies TT, Ekkel SM, Bayly-Jones C, Pang SS, Conroy PJ, Ramm G, Radjainia M, Venugopal H, Whisstock JC, Dunstone MA. Spicer BA, et al. Among authors: venugopal h. Nat Commun. 2018 Aug 15;9(1):3266. doi: 10.1038/s41467-018-05717-0. Nat Commun. 2018. PMID: 30111885 Free PMC article.

10

Atomic structures of an entire contractile injection system in both the extended and contracted states.

Desfosses A, Venugopal H, Joshi T, Felix J, Jessop M, Jeong H, Hyun J, Heymann JB, Hurst MRH, Gutsche I, Mitra AK. Desfosses A, et al. Among authors: venugopal h. Nat Microbiol. 2019 Nov;4(11):1885-1894. doi: 10.1038/s41564-019-0530-6. Epub 2019 Aug 5. Nat Microbiol. 2019. PMID: 31384001 Free PMC article.

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