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Page 1
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
Caswell DR, Gui P, Mayekar MK, Law EK, Pich O, Bailey C, Boumelha J, Kerr DL, Blakely CM, Manabe T, Martinez-Ruiz C, Bakker B, De Dios Palomino Villcas J, I Vokes N, Dietzen M, Angelova M, Gini B, Tamaki W, Allegakoen P, Wu W, Humpton TJ, Hill W, Tomaschko M, Lu WT, Haderk F, Al Bakir M, Nagano A, Gimeno-Valiente F, de Carné Trécesson S, Vendramin R, Barbè V, Mugabo M, Weeden CE, Rowan A, McCoach CE, Almeida B, Green M, Gomez C, Nanjo S, Barbosa D, Moore C, Przewrocka J, Black JRM, Grönroos E, Suarez-Bonnet A, Priestnall SL, Zverev C, Lighterness S, Cormack J, Olivas V, Cech L, Andrews T, Rule B, Jiao Y, Zhang X, Ashford P, Durfee C, Venkatesan S, Temiz NA, Tan L, Larson LK, Argyris PP, Brown WL, Yu EA, Rotow JK, Guha U, Roper N, Yu J, Vogel RI, Thomas NJ, Marra A, Selenica P, Yu H, Bakhoum SF, Chew SK, Reis-Filho JS, Jamal-Hanjani M, Vousden KH, McGranahan N, Van Allen EM, Kanu N, Harris RS, Downward J, Bivona TG, Swanton C. Caswell DR, et al. Among authors: venkatesan s. Nat Genet. 2024 Jan;56(1):60-73. doi: 10.1038/s41588-023-01592-8. Epub 2023 Dec 4. Nat Genet. 2024. PMID: 38049664 Free PMC article.
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer.
Kanu N, Cerone MA, Goh G, Zalmas LP, Bartkova J, Dietzen M, McGranahan N, Rogers R, Law EK, Gromova I, Kschischo M, Walton MI, Rossanese OW, Bartek J, Harris RS, Venkatesan S, Swanton C. Kanu N, et al. Among authors: venkatesan s. Genome Biol. 2016 Sep 15;17(1):185. doi: 10.1186/s13059-016-1042-9. Genome Biol. 2016. PMID: 27634334 Free PMC article.
Constraints in cancer evolution.
Venkatesan S, Birkbak NJ, Swanton C. Venkatesan S, et al. Biochem Soc Trans. 2017 Feb 8;45(1):1-13. doi: 10.1042/BST20160229. Biochem Soc Trans. 2017. PMID: 28202655 Review.
Chromosomal instability drives metastasis through a cytosolic DNA response.
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Bakhoum SF, et al. Among authors: venkatesan s. Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432. Epub 2018 Jan 17. Nature. 2018. PMID: 29342134 Free PMC article.
Evolutionary dynamics in pre-invasive neoplasia.
Abbosh C, Venkatesan S, Janes SM, Fitzgerald RC, Swanton C. Abbosh C, et al. Among authors: venkatesan s. Curr Opin Syst Biol. 2017 Apr;2:1-8. doi: 10.1016/j.coisb.2017.02.009. Curr Opin Syst Biol. 2017. PMID: 30603736 Free PMC article.
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu WT, Dietzen M, Galanos P, Evangelou K, Bellelli R, Lim EL, Watkins TBK, Rowan A, Teixeira VH, Zhao Y, Chen H, Ngo B, Zalmas LP, Al Bakir M, Hobor S, Grönroos E, Pennycuick A, Nigro E, Campbell BB, Brown WL, Akarca AU, Marafioti T, Wu MY, Howell M, Boulton SJ, Bertoli C, Fenton TR, de Bruin RAM, Maya-Mendoza A, Santoni-Rugiu E, Hynds RE, Gorgoulis VG, Jamal-Hanjani M, McGranahan N, Harris RS, Janes SM, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C; TRACERx Consortium. Venkatesan S, et al. Cancer Discov. 2021 Oct;11(10):2456-2473. doi: 10.1158/2159-8290.CD-20-0725. Epub 2021 May 4. Cancer Discov. 2021. PMID: 33947663 Free PMC article.
APOBEC3 as a driver of genetic intratumor heterogeneity.
Venkatesan S, Angelova M, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C. Venkatesan S, et al. Mol Cell Oncol. 2022 Jan 3;10(1):2014734. doi: 10.1080/23723556.2021.2014734. eCollection 2023. Mol Cell Oncol. 2022. PMID: 38116246 Free PMC article.
530 results