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Transplanted organoids empower human preclinical assessment of drug candidate for the clinic.
Westerling-Bui AD, Fast EM, Soare TW, Venkatachalan S, DeRan M, Fanelli AB, Kyrychenko S, Hoang H, Corriea GM, Zhang W, Yu M, Daniels M, Malojcic G, Pan-Zhou XR, Ledeboer MW, Harmange JC, Emani M, Tibbitts TT, Reilly JF, Mundel P. Westerling-Bui AD, et al. Among authors: venkatachalan s. Sci Adv. 2022 Jul 8;8(27):eabj5633. doi: 10.1126/sciadv.abj5633. Epub 2022 Jul 6. Sci Adv. 2022. PMID: 35857479 Free PMC article.
Discovery and Optimization of Highly Selective Inhibitors of CDK5.
Daniels MH, Malojcic G, Clugston SL, Williams B, Coeffet-Le Gal M, Pan-Zhou XR, Venkatachalan S, Harmange JC, Ledeboer M. Daniels MH, et al. Among authors: venkatachalan s. J Med Chem. 2022 Feb 24;65(4):3575-3596. doi: 10.1021/acs.jmedchem.1c02069. Epub 2022 Feb 10. J Med Chem. 2022. PMID: 35143203
Identification of a fluorescent general anesthetic, 1-aminoanthracene.
Butts CA, Xi J, Brannigan G, Saad AA, Venkatachalan SP, Pearce RA, Klein ML, Eckenhoff RG, Dmochowski IJ. Butts CA, et al. Among authors: venkatachalan sp. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6501-6. doi: 10.1073/pnas.0810590106. Epub 2009 Apr 3. Proc Natl Acad Sci U S A. 2009. PMID: 19346473 Free PMC article.
Functional group interactions of a 5-HT3R antagonist.
Venkataraman P, Joshi P, Venkatachalan SP, Muthalagi M, Parihar HS, Kirschbaum KS, Schulte MK. Venkataraman P, et al. Among authors: venkatachalan sp. BMC Biochem. 2002 Jun 13;3:16. doi: 10.1186/1471-2091-3-16. Epub 2002 Jun 13. BMC Biochem. 2002. PMID: 12079499 Free PMC article.