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Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
Milanski M, Degasperi G, Coope A, Morari J, Denis R, Cintra DE, Tsukumo DM, Anhe G, Amaral ME, Takahashi HK, Curi R, Oliveira HC, Carvalheira JB, Bordin S, Saad MJ, Velloso LA. Milanski M, et al. Among authors: velloso la. J Neurosci. 2009 Jan 14;29(2):359-70. doi: 10.1523/JNEUROSCI.2760-08.2009. J Neurosci. 2009. PMID: 19144836 Free PMC article.
Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats.
Ropelle ER, Pauli JR, Prada P, Cintra DE, Rocha GZ, Moraes JC, Frederico MJ, da Luz G, Pinho RA, Carvalheira JB, Velloso LA, Saad MA, De Souza CT. Ropelle ER, et al. Among authors: velloso la. J Physiol. 2009 May 15;587(Pt 10):2341-51. doi: 10.1113/jphysiol.2009.170050. Epub 2009 Mar 30. J Physiol. 2009. PMID: 19332486 Free PMC article.
High-fat diet induces apoptosis of hypothalamic neurons.
Moraes JC, Coope A, Morari J, Cintra DE, Roman EA, Pauli JR, Romanatto T, Carvalheira JB, Oliveira AL, Saad MJ, Velloso LA. Moraes JC, et al. Among authors: velloso la. PLoS One. 2009;4(4):e5045. doi: 10.1371/journal.pone.0005045. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340313 Free PMC article.
Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis.
Romanatto T, Roman EA, Arruda AP, Denis RG, Solon C, Milanski M, Moraes JC, Bonfleur ML, Degasperi GR, Picardi PK, Hirabara S, Boschero AC, Curi R, Velloso LA. Romanatto T, et al. Among authors: velloso la. J Biol Chem. 2009 Dec 25;284(52):36213-36222. doi: 10.1074/jbc.M109.030874. Epub 2009 Oct 26. J Biol Chem. 2009. PMID: 19858212 Free PMC article. Retracted.
383 results