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Discovery of potent macrocyclic HCV NS5A inhibitors.
Bioorg Med Chem Lett. 2016 Aug 1;26(15):3793-9. doi: 10.1016/j.bmcl.2016.05.042. Epub 2016 May 17.
Bioorg Med Chem Lett. 2016.
PMID: 27282743
4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.
Pechulis AD, Beck JP, Curry MA, Wolf MA, Harms AE, Xi N, Opalka C, Sweet MP, Yang Z, Vellekoop AS, Klos AM, Crocker PJ, Hassler C, Laws M, Kitchen DB, Smith MA, Olson RE, Liu S, Molino BF.
Pechulis AD, et al. Among authors: vellekoop as.
Bioorg Med Chem Lett. 2012 Dec 1;22(23):7219-22. doi: 10.1016/j.bmcl.2012.09.050. Epub 2012 Sep 25.
Bioorg Med Chem Lett. 2012.
PMID: 23084899
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Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.
Gurney ME, Nugent RA, Mo X, Sindac JA, Hagen TJ, Fox D 3rd, O'Donnell JM, Zhang C, Xu Y, Zhang HT, Groppi VE, Bailie M, White RE, Romero DL, Vellekoop AS, Walker JR, Surman MD, Zhu L, Campbell RF.
Gurney ME, et al. Among authors: vellekoop as.
J Med Chem. 2019 May 23;62(10):4884-4901. doi: 10.1021/acs.jmedchem.9b00193. Epub 2019 Apr 23.
J Med Chem. 2019.
PMID: 31013090
Free PMC article.
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A new chemical tool for exploring the physiological function of the PDE2 isozyme.
Chambers RJ, Abrams K, Garceau NY, Kamath AV, Manley CM, Lilley SC, Otte DA, Scott DO, Sheils AL, Tess DA, Vellekoop AS, Zhang Y, Lam KT.
Chambers RJ, et al. Among authors: vellekoop as.
Bioorg Med Chem Lett. 2006 Jan 15;16(2):307-10. doi: 10.1016/j.bmcl.2005.10.005. Epub 2005 Nov 3.
Bioorg Med Chem Lett. 2006.
PMID: 16275071
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Preparation of Chiral Oxazolidin-2-ones and Vicinal Amino Alcohols.
Takacs JM, Jaber MR, Vellekoop AS.
Takacs JM, et al. Among authors: vellekoop as.
J Org Chem. 1998 Apr 17;63(8):2742-2748. doi: 10.1021/jo9720804.
J Org Chem. 1998.
PMID: 11672148
No abstract available.
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