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Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.
Nat Genet. 2010 Jan;42(1):89-93. doi: 10.1038/ng.494. Epub 2009 Dec 20.
Nat Genet. 2010.
PMID: 20023660
Free PMC article.
WT1 regulates the expression of inhibitory chemokines during heart development.
Velecela V, Lettice LA, Chau YY, Slight J, Berry RL, Thornburn A, Gunst QD, van den Hoff M, Reina M, Martínez FO, Hastie ND, Martínez-Estrada OM.
Velecela V, et al.
Hum Mol Genet. 2013 Dec 20;22(25):5083-95. doi: 10.1093/hmg/ddt358. Epub 2013 Jul 29.
Hum Mol Genet. 2013.
PMID: 23900076
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Biological Systems and Methods for Studying WT1 in the Epicardium.
Velecela V, Fazal-Salom J, Martínez-Estrada OM.
Velecela V, et al.
Methods Mol Biol. 2016;1467:61-71. doi: 10.1007/978-1-4939-4023-3_5.
Methods Mol Biol. 2016.
PMID: 27417959
Review.
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Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4.
Velecela V, Torres-Cano A, García-Melero A, Ramiro-Pareta M, Müller-Sánchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martínez FO, Martínez-Estrada OM.
Velecela V, et al.
Development. 2019 Oct 17;146(20):dev178723. doi: 10.1242/dev.178723.
Development. 2019.
PMID: 31624071
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Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2.
Guadix JA, Ruiz-Villalba A, Lettice L, Velecela V, Muñoz-Chápuli R, Hastie ND, Pérez-Pomares JM, Martínez-Estrada OM.
Guadix JA, et al. Among authors: velecela v.
Development. 2011 Mar;138(6):1093-7. doi: 10.1242/dev.044594.
Development. 2011.
PMID: 21343363
Free PMC article.
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A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression.
Essafi A, Webb A, Berry RL, Slight J, Burn SF, Spraggon L, Velecela V, Martinez-Estrada OM, Wiltshire JH, Roberts SG, Brownstein D, Davies JA, Hastie ND, Hohenstein P.
Essafi A, et al. Among authors: velecela v.
Dev Cell. 2011 Sep 13;21(3):559-74. doi: 10.1016/j.devcel.2011.07.014. Epub 2011 Aug 25.
Dev Cell. 2011.
PMID: 21871842
Free PMC article.
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The proepicardium keeps a potential for glomerular marker expression which supports its evolutionary origin from the pronephros.
Cano E, Carmona R, Velecela V, Martínez-Estrada O, Muñoz-Chápuli R.
Cano E, et al. Among authors: velecela v.
Evol Dev. 2015 Jul-Aug;17(4):224-30. doi: 10.1111/ede.12130.
Evol Dev. 2015.
PMID: 26174098
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