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Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.
Martínez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Muñoz-Chapuli R, Hastie ND. Martínez-Estrada OM, et al. Among authors: velecela v. Nat Genet. 2010 Jan;42(1):89-93. doi: 10.1038/ng.494. Epub 2009 Dec 20. Nat Genet. 2010. PMID: 20023660 Free PMC article.
WT1 regulates the expression of inhibitory chemokines during heart development.
Velecela V, Lettice LA, Chau YY, Slight J, Berry RL, Thornburn A, Gunst QD, van den Hoff M, Reina M, Martínez FO, Hastie ND, Martínez-Estrada OM. Velecela V, et al. Hum Mol Genet. 2013 Dec 20;22(25):5083-95. doi: 10.1093/hmg/ddt358. Epub 2013 Jul 29. Hum Mol Genet. 2013. PMID: 23900076