Velcich A - Search Results

1

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.

Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC. Johansson ME, et al. Among authors: velcich a. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15064-9. doi: 10.1073/pnas.0803124105. Epub 2008 Sep 19. Proc Natl Acad Sci U S A. 2008. PMID: 18806221 Free PMC article.

2

Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis.

Wenzel UA, Magnusson MK, Rydström A, Jonstrand C, Hengst J, Johansson ME, Velcich A, Öhman L, Strid H, Sjövall H, Hansson GC, Wick MJ. Wenzel UA, et al. Among authors: velcich a. PLoS One. 2014 Jun 19;9(6):e100217. doi: 10.1371/journal.pone.0100217. eCollection 2014. PLoS One. 2014. PMID: 24945909 Free PMC article.

3

Importance and regulation of the colonic mucus barrier in a mouse model of colitis.

Petersson J, Schreiber O, Hansson GC, Gendler SJ, Velcich A, Lundberg JO, Roos S, Holm L, Phillipson M. Petersson J, et al. Among authors: velcich a. Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G327-33. doi: 10.1152/ajpgi.00422.2010. Epub 2010 Nov 25. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21109593 Free PMC article.

4

Colorectal cancer in mice genetically deficient in the mucin Muc2.

Velcich A, Yang W, Heyer J, Fragale A, Nicholas C, Viani S, Kucherlapati R, Lipkin M, Yang K, Augenlicht L. Velcich A, et al. Science. 2002 Mar 1;295(5560):1726-9. doi: 10.1126/science.1069094. Science. 2002. PMID: 11872843

5

Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa.

Bergstrom KS, Kissoon-Singh V, Gibson DL, Ma C, Montero M, Sham HP, Ryz N, Huang T, Velcich A, Finlay BB, Chadee K, Vallance BA. Bergstrom KS, et al. Among authors: velcich a. PLoS Pathog. 2010 May 13;6(5):e1000902. doi: 10.1371/journal.ppat.1000902. PLoS Pathog. 2010. PMID: 20485566 Free PMC article.

6

The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis.

Zarepour M, Bhullar K, Montero M, Ma C, Huang T, Velcich A, Xia L, Vallance BA. Zarepour M, et al. Among authors: velcich a. Infect Immun. 2013 Oct;81(10):3672-83. doi: 10.1128/IAI.00854-13. Epub 2013 Jul 22. Infect Immun. 2013. PMID: 23876803 Free PMC article.

7

Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice.

van der Sluis M, Bouma J, Vincent A, Velcich A, Carraway KL, Büller HA, Einerhand AW, van Goudoever JB, Van Seuningen I, Renes IB. van der Sluis M, et al. Among authors: velcich a. Lab Invest. 2008 Jun;88(6):634-42. doi: 10.1038/labinvest.2008.28. Epub 2008 Apr 21. Lab Invest. 2008. PMID: 18427556 Free article.

8

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection.

Van der Sluis M, De Koning BA, De Bruijn AC, Velcich A, Meijerink JP, Van Goudoever JB, Büller HA, Dekker J, Van Seuningen I, Renes IB, Einerhand AW. Van der Sluis M, et al. Among authors: velcich a. Gastroenterology. 2006 Jul;131(1):117-29. doi: 10.1053/j.gastro.2006.04.020. Gastroenterology. 2006. PMID: 16831596

9

Threonine metabolism in the intestine of mice: loss of mucin 2 induces the threonine catabolic pathway.

van der Sluis M, Schaart MW, de Koning BA, Schierbeek H, Velcich A, Renes IB, van Goudoever JB. van der Sluis M, et al. Among authors: velcich a. J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):99-107. doi: 10.1097/MPG.0b013e3181a23dbe. J Pediatr Gastroenterol Nutr. 2009. PMID: 19502996

10

Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals.

Shan M, Gentile M, Yeiser JR, Walland AC, Bornstein VU, Chen K, He B, Cassis L, Bigas A, Cols M, Comerma L, Huang B, Blander JM, Xiong H, Mayer L, Berin C, Augenlicht LH, Velcich A, Cerutti A. Shan M, et al. Among authors: velcich a. Science. 2013 Oct 25;342(6157):447-53. doi: 10.1126/science.1237910. Epub 2013 Sep 26. Science. 2013. PMID: 24072822 Free PMC article.

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